product summary
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company name :
MyBioSource
product type :
antibody
product name :
IL18 Polyclonal Antibody
catalog :
MBS2525595
quantity :
0.02 mL
price :
110 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
image
image 1 :
MyBioSource MBS2525595 image 1
Western Blot analysis of Hela cells using IL18 Polyclonal Antibody at dilution of 1:1350
image 2 :
MyBioSource MBS2525595 image 2
Immunohistochemistry of paraffin-embedded Human ovarian cancer using IL18 Polyclonal Antibody at dilution of 1:100
image 3 :
MyBioSource MBS2525595 image 3
Immunohistochemistry of paraffin-embedded Human cervical cancer using IL18 Polyclonal Antibody at dilution of 1:100
product information
catalog number :
MBS2525595
products type :
Antibody
products full name :
IL18 Polyclonal Antibody
products short name :
[IL18]
products name syn :
[IGIF, IL-18, IL-1g, IL1F4]
other names :
[IL18, partial; Interleukin-18; interleukin-18; IFN-gamma-inducing factor; IL-1 gamma; iboctadekin; interleukin 18 (interferon-gamma-inducing factor); interleukin-1 gamma; interleukin 18; Iboctadekin; Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; IL-1 gamma]
products gene name :
[IL18]
other gene names :
[IL18; IL18; IGIF; IL-18; IL-1g; IL1F4; IGIF; IL1F4; IL-18; IFN-gamma-inducing factor; IL-1 gamma]
uniprot entry name :
IL18_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
193
purity :
Affinity purification
concentration :
0.3mg/mL
storage stability :
Store at -20°C. Avoid freeze / thaw cycles.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:1000-1:2000. IHC: 1:100-1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Recombinant protein of human IL18
other info2 :
Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3
products categories :
Cancer
products description :
The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon gamma production in T-helper type I cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene
ncbi gi num :
49456955
ncbi acc num :
BC007007
uniprot acc num :
Q14116
ncbi mol weight :
22kDa
ncbi pathways :
African Trypanosomiasis Pathway (194384); African Trypanosomiasis Pathway (194323); Cellular Roles Of Anthrax Toxin Pathway (138076); Corticotropin-releasing Hormone Pathway (920957); Cytokine Signaling In Immune System Pathway (366171); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Cytosolic DNA-sensing Pathway (125137); Cytosolic DNA-sensing Pathway (124833); Hypertrophy Model Pathway (198828)
ncbi summary :
The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon gamma production in T-helper type I cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011]
uniprot summary :
IL18: Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. Belongs to the IL-1 family. Protein type: Cytokine. Chromosomal Location of Human Ortholog: 11q22.2-q22.3. Cellular Component: extracellular space; extracellular region; cytosol. Molecular Function: protein binding; cytokine activity. Biological Process: positive regulation of granulocyte macrophage colony-stimulating factor production; positive regulation of interleukin-17 production; regulation of cell adhesion; positive regulation of natural killer cell proliferation; T-helper 1 type immune response; T-helper 2 type immune response; interleukin-2 biosynthetic process; MAPKKK cascade; positive regulation of NK T cell proliferation; interleukin-13 biosynthetic process; natural killer cell activation; positive regulation of NF-kappaB import into nucleus; positive regulation of activated T cell proliferation; sleep; chemokine biosynthetic process; positive regulation of tissue remodeling; positive regulation of interferon-gamma production; cell-cell signaling; lipopolysaccharide-mediated signaling pathway; interferon-gamma biosynthetic process; granulocyte macrophage colony-stimulating factor biosynthetic process; immune response; angiogenesis; negative regulation of myoblast differentiation; inflammatory response; positive regulation of inflammatory response
size1 :
0.02 mL
price1 :
110 USD
size2 :
0.06 mL
price2 :
150
size3 :
0.12 mL
price3 :
225
size4 :
0.2 mL
price4 :
360
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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