catalog number :
MBS2524754
products full name :
CACNA1B Antibody
products short name :
CACNA1B
products name syn :
BIII, Brain calcium channel III, CACH5, CACNL1A5, CACNN, Cav2.2
products gene name :
CACNA1B
reactivity :
Human, Mouse, Rat
purity :
Antigen affinity purification
storage stability :
Store at -20 degree C. Avoid freeze / thaw cycles
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:200-1:1000. IHC: 1:20-1:200
other info1 :
Immunogen: Fusion protein of CACNAlB. Calculated MW: 262kd. Observed MW: 262kd
other info2 :
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
products description :
Background/Introduction: CACNA1B, also named as CACH5, CACNL1A5 and BIII, belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. CACNA1B gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by omega-conotoxin-GVIA (omega-CTx-GVIA) and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to dihydropyridines (DHP), and omega-agatoxin-IVA (omega-Aga-IVA). CACNA1B may play a role in directed migration of immature neurons.