catalog number :
MBS2524710
products full name :
CD9 Antibody
products short name :
[CD9]
products name syn :
[BTCC-1; DRAP-27; MIC3; MRP-1; TSPAN-29; TSPAN29]
other names :
[CD9 antigen; CD9 antigen; CD9 antigen; 5H9 antigen; BA-2/p24 antigen; CD9 antigen (p24); cell growth-inhibiting gene 2 protein; leukocyte antigen MIC3; motility related protein-1; tetraspanin-29; CD9 molecule; 5H9 antigen; Cell growth-inhibiting gene 2 protein; Leukocyte antigen MIC3; Motility-related protein; MRP-1; Tetraspanin-29; Tspan-29; p24; CD_antigen: CD9]
products gene name :
[CD9]
other gene names :
[CD9; CD9; MIC3; MRP-1; BTCC-1; DRAP-27; TSPAN29; TSPAN-29; MIC3; TSPAN29; MRP-1; Tspan-29]
uniprot entry name :
CD9_HUMAN
reactivity :
Human, Mouse
purity :
Antigen affinity purification
storage stability :
Store at -20 degree C. Avoid freeze
tested application :
Western Blot (WB)
app notes :
WB: 1:500 - 1:2000
image1 heading :
Western Blot (WB)
image2 heading :
Western Blot (WB)
image3 heading :
Immunohistochemistry (IHC)
image4 heading :
Immunohistochemistry (IHC)
image4 description :
Immunohistochemistry of paraffin-embedded human spleen hematoma using CD9 antibody at dilution of 1:100 (400x lens).
other info1 :
Immunogen: Recombinant protein of human CD9
other info2 :
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-7639 / sc-9148
products description :
This gene encodes a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins. The encoded protein functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression of this gene plays a critical role in the suppression of cancer cell motility and metastasis. [provided by RefSeq, Jan 2011]
ncbi acc num :
NP_001760.1
ncbi gb acc num :
NM_001769.3
ncbi mol weight :
Calculated MW: 25kDa. Observed MW: 25kDa
ncbi pathways :
Disease Pathway (530764); Fertilization Pathway (833797); Hematopoietic Cell Lineage Pathway (83078); Hematopoietic Cell Lineage Pathway (489); Hemostasis Pathway (106028); Platelet Activation, Signaling And Aggregation Pathway (106034); Platelet Degranulation Pathway (106050); Reproduction Pathway (833796); Response To Elevated Platelet Cytosolic Ca2+ Pathway (106048); Sperm:Oocyte Membrane Binding Pathway (833802)
ncbi summary :
This gene encodes a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins. The encoded protein functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression of this gene plays a critical role in the suppression of cancer cell motility and metastasis. [provided by RefSeq, Jan 2011]
uniprot summary :
CD9: Involved in platelet activation and aggregation. Regulates paranodal junction formation. Involved in cell adhesion, cell motility and tumor metastasis. Required for sperm-egg fusion. Belongs to the tetraspanin (TM4SF) family. Protein type: Motility/polarity/chemotaxis; Membrane protein, multi-pass; Membrane protein, integral; Cell adhesion. Chromosomal Location of Human Ortholog: 12p13.3. Cellular Component: extracellular space; platelet alpha granule membrane; focal adhesion; integral to plasma membrane; apical plasma membrane; plasma membrane; vesicle; external side of plasma membrane. Molecular Function: integrin binding; protein binding. Biological Process: platelet activation; fusion of sperm to egg plasma membrane; pathogenesis; multicellular organism reproduction; paranodal junction assembly; negative regulation of cell proliferation; platelet degranulation; single fertilization; brain development; blood coagulation; oligodendrocyte development; cell adhesion; cell motility; response to water deprivation