product summary
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company name :
MyBioSource
product type :
antibody
product name :
CERS1 Polyclonal Antibody
catalog :
MBS2523738
quantity :
0.02 mL
price :
110 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS2523738 image 1
Western Blot analysis of Hepg2 and hela cell using CERS1 Polyclonal Antibody at dilution of 1:200
image 2 :
MyBioSource MBS2523738 image 2
Immunohistochemistry of paraffin-embedded Human ovarian cancer using CERS1 Polyclonal Antibody at dilution of 1:20
image 3 :
MyBioSource MBS2523738 image 3
Immunohistochemistry of paraffin-embedded Human prostate cancer using CERS1 Polyclonal Antibody at dilution of 1:20
product information
catalog number :
MBS2523738
products type :
Antibody
products full name :
CERS1 Polyclonal Antibody
products short name :
[CERS1]
products name syn :
[LAG1; UOG1; LASS1]
other names :
[ceramide synthase 1 isoform 3; Ceramide synthase 1; ceramide synthase 1; longevity assurance (LAG1, S. cerevisiae) homolog 1; longevity assurance gene 1 protein homolog 1; protein UOG-1; upstream of GDF1; ceramide synthase 1; LAG1 longevity assurance homolog 1; Longevity assurance gene 1 protein homolog 1; Protein UOG-1]
products gene name :
[CERS1]
other gene names :
[CERS1; CERS1; LAG1; UOG1; LASS1; LAG1; LASS1; UOG1; CerS1]
uniprot entry name :
CERS1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse
purity :
Affinity purification
form :
PBS with 0.05% sodium azide, 50% glycerol, PH7.3
storage stability :
Store at -20 degree C. Avoid freeze / thaw cycles.
tested application :
Immunohistochemistry (IHC), Western Blot (WB), ELISA (EIA)
app notes :
WB 1:500-1:2000. IHC 1:50-1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Store at -20?. Avoid freeze / thaw cycles.
other info2 :
Immunogen: Synthetic peptide of human CERS1. Note: Centrifuge before opening to ensure complete recovery of vial contents.
products description :
This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues. Members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in yeast suggest that the encoded protein is involved in aging.
ncbi gi num :
594140567
ncbi acc num :
NP_067090
ncbi gb acc num :
NM_001290265.1
uniprot acc num :
P27544
ncbi mol weight :
40kDa
ncbi pathways :
Ceramide Biosynthesis Pathway (524496); Ceramide Biosynthesis Pathway (468287); Metabolic Pathways (132956); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Sphingolipid De Novo Biosynthesis Pathway (530750); Sphingolipid Metabolism Pathway (82994); Sphingolipid Metabolism Pathway (119543); Sphingolipid Metabolism Pathway (369); Sphingosine Biosynthesis Pathway (524497)
ncbi summary :
This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues. Members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in yeast suggest that the encoded protein is involved in aging. This protein is transcribed from a monocistronic mRNA as well as a bicistronic mRNA, which also encodes growth differentiation factor 1. [provided by RefSeq, Jul 2008]
uniprot summary :
LASS1: May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked stearoyl- (C18) ceramide) in a fumonisin B1-independent manner. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, multi-pass; Membrane protein, integral. Chromosomal Location of Human Ortholog: 19p12. Cellular Component: Golgi membrane; endoplasmic reticulum membrane; intracellular membrane-bound organelle; membrane; endoplasmic reticulum; integral to membrane. Molecular Function: sphingosine N-acyltransferase activity. Biological Process: negative regulation of telomerase activity; sphingolipid metabolic process; sphingolipid biosynthetic process; ceramide biosynthetic process. Disease: Epilepsy, Progressive Myoclonic, 8
size1 :
0.02 mL
price1 :
110 USD
size2 :
0.06 mL
price2 :
150
size3 :
0.12 mL
price3 :
225
size4 :
0.2 mL
price4 :
360
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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