catalog number :
MBS252213
products type :
Recombinant Protein
products full name :
Nucleoside diphosphate kinase A
products short name :
Nucleoside diphosphate kinase A
other names :
nucleoside diphosphate kinase A isoform b; Nucleoside diphosphate kinase A; nucleoside diphosphate kinase A; NDP kinase A; granzyme A-activated DNase; metastasis inhibition factor nm23; tumor metastatic process-associated protein; non-metastatic cells 1, protein (NM23A) expressed in; NME/NM23 nucleoside diphosphate kinase 1; Granzyme A-activated DNase; GAAD; Metastasis inhibition factor nm23; NM23-H1; Tumor metastatic process-associated protein
other gene names :
NME1; NME1; NB; AWD; NBS; GAAD; NDKA; NM23; NDPKA; NDPK-A; NM23-H1; NDPKA; NM23; NDK A; NDP kinase A; GAAD
uniprot entry name :
NDKA_HUMAN
sequence :
ANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKF
MQASEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWE
GLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIH
GSDSVESAEKEIGLWFHPEELVDYTSCAQNWIYE-
concentration :
0.2 mg/ml
other info1 :
Tag Information: GST tag
other info2 :
Organism: Homo sapiens (Human). Storage Buffer: 20mM Tris-HCI, O.5M Arg, PH 8.0,50% glycerol
ncbi acc num :
NP_000260.1
ncbi gb acc num :
NM_000269.2
ncbi pathways :
Adenine Ribonucleotide Biosynthesis, IMP = ADP,ATP Pathway 618580!!Adenine Ribonucleotide Biosynthesis, IMP = ADP,ATP Pathway 468242!!Arf6 Downstream Pathway 138038!!Arf6 Trafficking Events Pathway 137954!!CMP Phosphorylation Pathway 908070!!E-cadherin Signaling In The Nascent Adherens Junction Pathway 138005!!Guanine Ribonucleotide Biosynthesis IMP = GDP,GTP Pathway 618581!!Guanine Ribonucleotide Biosynthesis IMP = GDP,GTP Pathway 468243!!Integrated Pancreatic Cancer Pathway 711360!!Metabolic Pathways 132956
ncbi summary :
This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Jul 2008]