product summary
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company name :
MyBioSource
product type :
antibody
product name :
DPEP1 Antibody
catalog :
MBS2521928
quantity :
0.06 mL
price :
195 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
image
image 1 :
MyBioSource MBS2521928 image 1
Wwestern Blot of Mouse liver tissue, using DPEP1 Polyclonal Antibody at dilution of 1:300
image 2 :
MyBioSource MBS2521928 image 2
Immunohistochemistry of paraffin-embedded human kidney tissue slide using DPEP1 Polyclonal Antibody at dilution of 1:200
product information
catalog number :
MBS2521928
products type :
Antibody
products full name :
DPEP1 Antibody
products short name :
[DPEP1]
products name syn :
[Dehydropeptidase I, Dipeptidase 1, dipeptidase 1,(renal), DPEP1, hRDP, MBD1, MDP, Microsomal,ipeptidase, RDP, Renal dipeptidase.]
other names :
[dipeptidase 1; Dipeptidase 1; dipeptidase 1; dehydropeptidase-I; hRDP; microsomal dipeptidase; renal dipeptidase; dipeptidase 1 (renal); Dehydropeptidase-I; Microsomal dipeptidase; Renal dipeptidase; hRDP]
products gene name :
[DPEP1]
other gene names :
[DPEP1; DPEP1; MDP; RDP; MBD1; MDP; RDP; hRDP]
uniprot entry name :
DPEP1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
411
purity :
Antigen affinity purification
form :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
storage stability :
Store at -20°C. Avoid freeze / thaw cycles
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:200-1:1000 . IHC: 1:100-1:400
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Fusion protein of DPEP1 . Calculated MW: 411aa,46 kDa . Observed MW: 46kd
other info2 :
Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-109262 / sc-109260
products description :
DPEP1(Dipeptidase 1) is also named as MDP, RDP and belongs to the peptidase M19 family. It is a glycoprotein that playis an important role in he regulation of leukotriene activity. DPEP1 converts lekotriene D4 to leukotriene E4.
ncbi gi num :
189458885
ncbi acc num :
BC017023
ncbi gb acc num :
NM_001128141.2
uniprot acc num :
Q9UM19
ncbi pathways :
Aflatoxin Activation And Detoxification Pathway (1127511); Arachidonic Acid Metabolism Pathway (685553); Biological Oxidations Pathway (105698); Defective ACY1 Causes Encephalopathy Pathway (1127638); Disease Pathway (530764); Eicosanoid Synthesis Pathway (198888); Metabolic Disorders Of Biological Oxidation Enzymes Pathway (1127637); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Synthesis Of Leukotrienes (LT) And Eoxins (EX) Pathway (730334)
ncbi summary :
The protein encoded by this gene is a kidney membrane enzyme involved in the metabolism of glutathione and other similar proteins by dipeptide hydrolysis. The encoded protein is known to regulate leukotriene activity by catalyzing the conversion of leukotriene D4 to leukotriene E4. This protein uses zinc as a cofactor and acts as a disulfide-linked homodimer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2012]
uniprot summary :
DPEP1: Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity. Belongs to the peptidase M19 family. Protein type: EC 3.4.13.19; Membrane protein, GPI anchor; Protease. Chromosomal Location of Human Ortholog: 16q24.3. Cellular Component: extracellular space; microvillus membrane; apical part of cell; apical plasma membrane; plasma membrane; nucleus; cell junction. Molecular Function: protein binding; metalloexopeptidase activity; zinc ion binding; dipeptidyl-peptidase activity; caspase inhibitor activity. Biological Process: glutathione metabolic process; xenobiotic metabolic process; arachidonic acid metabolic process; leukotriene metabolic process; homocysteine metabolic process; negative regulation of caspase activity; proteolysis; negative regulation of cell migration; antibiotic metabolic process; negative regulation of apoptosis
size1 :
0.06 mL
price1 :
195 USD
size2 :
0.12 mL
price2 :
270
size3 :
0.2 mL
price3 :
435
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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