product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
KLK2 Antibody
catalog :
MBS2521782
quantity :
0.06 mL
price :
195 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
image
image 1 :
mouse pancreas tissue were subjected to SDS PAGE followed by western blot with KLK2 Antibndy at dilution of I :300
image 2 :
Immunohistochemical of paraffin-embedded human prostate cancer using KLK2 antibody at dilution of 1:100 (under lOx lens)
product information
catalog number :
MBS2521782
products type :
Antibody
products full name :
KLK2 Antibody
products short name :
[KLK2]
products name syn :
[KLK2A2; MGC12201; hK2]
other names :
[kallikrein-2 isoform 3; Kallikrein-2; kallikrein-2; glandular kallikrein 2; glandular kallikrein-1; kallikrein 2, prostatic; tissue kallikrein-2; kallikrein-related peptidase 2; Glandular kallikrein-1; hGK-1; Tissue kallikrein-2]
products gene name :
[KLK2]
other gene names :
[KLK2; KLK2; hK2; hGK-1; KLK2A2; hGK-1]
uniprot entry name :
KLK2_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse
sequence length :
159
purity :
Antigen affinity purification
storage stability :
Store at -20 degree C. Avoid freeze / thaw cycles
tested application :
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
app notes :
WB: 1:200-1:1000. IHC: 1:20-1:200
image1 heading :
SDS-PAGE
image2 heading :
Immunohistochemistry
other info1 :
Immunogen: Fusion protein of KLK2. Calculated Molecular Weight: 28kd. Observed Molecular Weight: 29kD
other info2 :
Buffer: PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-20368
products description :
KLK2(Kallikrein-2) is also named as hGK-l and belongs to the Kallikrein subfamily. It plays a role in prostate cancer susceptibility and this role may be realized at least in part by the induction of increases in its production. It also may mediate tumor growth and invasion by participating in proteolytic cascades. This protein has 4 isoforms produced by alternative splicing with the molecular weight of 29 kDa, 25 kDa, 18 kDa and 17 kDa.
ncbi gi num :
368710110
ncbi acc num :
NP_001243009.1
ncbi gb acc num :
NM_001256080.1
uniprot acc num :
P20151
ncbi pathways :
Activation Of Matrix Metalloproteinases Pathway (576264); Coregulation Of Androgen Receptor Activity Pathway (138085); Degradation Of The Extracellular Matrix Pathway (576263); Endocrine And Other Factor-regulated Calcium Reabsorption Pathway (213307); Endocrine And Other Factor-regulated Calcium Reabsorption Pathway (213276); Extracellular Matrix Organization Pathway (576262); Metabolism Of Proteins Pathway (106230); Prostate Cancer Pathway (755440); Regulation Of Androgen Receptor Activity Pathway (138027); Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway (105908)
ncbi summary :
This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Jan 2012]
uniprot summary :
KLK2: Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Belongs to the peptidase S1 family. Kallikrein subfamily. 3 isoforms of the human protein are produced by alternative splicing. Protein type: EC 3.4.21.35; Protease. Chromosomal Location of Human Ortholog: 19q13.41. Cellular Component: extracellular region. Molecular Function: serine-type endopeptidase activity. Biological Process: extracellular matrix disassembly; extracellular matrix organization and biogenesis; proteolysis
size1 :
0.06 mL
price1 :
195 USD
size2 :
0.12 mL
price2 :
270
size3 :
0.2 mL
price3 :
435
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!
related products
browse more products
questions and comments