product summary
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company name :
MyBioSource
product type :
antibody
product name :
AMIGO2 Polyclonal Antibody
catalog :
MBS2521654
quantity :
0.02 mL
price :
110 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
image
image 1 :
Western Blot analysis of SP20 cell and Mouse heart tissue using AMIGO2 Polyclonal Antibody at dilution of 1:615
image 2 :
Immunohistochemistry of paraffin-embedded Human esophagus cancer using AMIGO2 Polyclonal Antibody at dilution of 1:50
image 3 :
Immunohistochemistry of paraffin-embedded Human breast cancer using AMIGO2 Polyclonal Antibody at dilution of 1:50
product information
catalog number :
MBS2521654
products type :
Antibody
products full name :
AMIGO2 Polyclonal Antibody
products short name :
[AMIGO2]
products name syn :
[ALI1,DEGA,AMIGO-2]
other names :
[amphoterin-induced protein 2; Amphoterin-induced protein 2; amphoterin-induced protein 2; AMIGO2; alivin 1; amphoterin induced gene 2; differentially expressed in gastric adenocarcinoma; differentially expressed in gastric adenocarcinomas; transmembrane protein AMIGO2; adhesion molecule with Ig-like domain 2; AMIGO-2; Alivin-1; Differentially expressed in gastric adenocarcinomas; DEGA]
products gene name :
[AMIGO2]
other gene names :
[AMIGO2; AMIGO2; ALI1; DEGA; AMIGO-2; DEGA]
uniprot entry name :
AMGO2_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
purity :
affinity purification
storage stability :
Store at -20 degree C. Avoid freeze / thaw cycles.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:500-1:2000. IHC: 1:50-1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Recombinant protein of human AMIGO2
other info2 :
Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. Note: Centrifuge before opening to ensure complete recovery of vial contents.
products description :
The amphoterin-induced gene and ORF (AMIGO) family of proteins consists of AMIGO-1, AMIGO-2 and AMIGO-3. All three members are single pass type I membrane proteins that contain several leucine-rich repeats, one IgG domain, and a transmembrane domain. The AMIGO proteins are specifically expressed on fiber tracts of neuronal tissues and participate in their formation. The AMIGO proteins can form complexes with each other, but can also bind itself. AMIGO-1, also designated Alivin-2, promotes growth and fasciculation of neurites and plays a role in myelination and fasciculation of developing neural axons. In cerebellar neurons, AMIGO-2 (Alivin-1) is crucial for depolarization-dependent survival. Similar to AMIGO-1 and AMIGO-2, AMIGO-3 (Alivin-3) plays a role in homophilic and/or heterophilic cell-cell interaction and signal transduction
ncbi gi num :
219521831
ncbi acc num :
BC047595
ncbi gb acc num :
NM_001143668.1
uniprot acc num :
Q86SJ2
ncbi mol weight :
58kDa
uniprot summary :
AMIGO2: Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas. Belongs to the immunoglobulin superfamily. AMIGO family. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 12q13.11. Cellular Component: integral to membrane; plasma membrane; nucleus. Molecular Function: protein binding. Biological Process: heterophilic cell adhesion; negative regulation of programmed cell death; brain development; homophilic cell adhesion; negative regulation of apoptosis
size1 :
0.02 mL
price1 :
110 USD
size2 :
0.06 mL
price2 :
150
size3 :
0.12 mL
price3 :
225
size4 :
0.2 mL
price4 :
360
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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