product summary
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company name :
MyBioSource
product type :
antibody
product name :
CD177 Polyclonal Antibody
catalog :
MBS2521161
quantity :
0.02 mL
price :
110 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
image
image 1 :
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CD177 Polyclonal Antibody at dilution 1:30
image 2 :
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CD177 Polyclonal Antibody at dilution 1:30
product information
catalog number :
MBS2521161
products type :
Antibody
products full name :
CD177 Polyclonal Antibody
products short name :
[CD177]
products name syn :
[NB1; PRV1; HNA2A; PRV-1; HNA-2a; NB1 GP]
other names :
[CD177 antigen; CD177 antigen; CD177 antigen; NB1 glycoprotein; cell surface receptor; human neutrophil alloantigen 2a; polycythemia rubra vera protein 1; CD177 molecule; Human neutrophil alloantigen 2a; HNA-2a; NB1 glycoprotein; NB1 GP; Polycythemia rubra vera protein 1; PRV-1; CD_antigen: CD177]
products gene name :
[CD177]
other gene names :
[CD177; CD177; NB1; PRV1; HNA2A; PRV-1; HNA-2a; NB1 GP; NB1; PRV1; HNA-2a; NB1 GP; PRV-1]
uniprot entry name :
CD177_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
437
purity :
Affinity purification
concentration :
0.5mg/mL
storage stability :
Store at -20 degree C. Avoid freeze/thaw cycles.
tested application :
ELISA (EIA), Immunohistochemistry (IHC)
app notes :
IHC: 1:25-1:100
image1 heading :
Immunohistochemistry (IHC)
image2 heading :
Immunohistochemistry (IHC)
products categories :
Epigenetics
products description :
Background: NB1, a glycosyl-phosphatidylinositol (GPI)-linked N-glycosylated cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia. Highly expressed in normal bone marrow and weakly expressed in fetal liver. Expressed on neutrophils. Expressed in granulocytes of patients with polycythemia vera (PV) and with essential thrombocythemia (ET).
ncbi gi num :
110735433
ncbi acc num :
NP_065139.2
ncbi gb acc num :
NM_020406.3
uniprot acc num :
BC029167
ncbi pathways :
Cell Surface Interactions At The Vascular Wall Pathway (106062); Common Pathway (106060); Formation Of Fibrin Clot (Clotting Cascade) Pathway (106057); Hemostasis Pathway (106028)
ncbi summary :
This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified. [provided by RefSeq, Apr 2014]
uniprot summary :
CD177: Induced by CSF3 in resting granulocytes. Induced in patients with polycythemia vera (PV) and with essential thrombocythemia (ET). 3 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, GPI anchor. Chromosomal Location of Human Ortholog: 19q13.2. Cellular Component: plasma membrane. Biological Process: blood coagulation; leukocyte migration
size1 :
0.02 mL
price1 :
110 USD
size2 :
0.06 mL
price2 :
150
size3 :
0.12 mL
price3 :
225
size4 :
0.2 mL
price4 :
360
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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