product summary
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company name :
MyBioSource
product type :
antibody
product name :
IFT140 Antibody
catalog :
MBS2520225
quantity :
0.06 mL
price :
195 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunocytochemistry, enzyme immunoassay
more info or order :
image
image 1 :
Mouse testis tissue were subjected to SDS PAGE followed by western blot with IFT140 antibody at dilution of 1:300
product information
catalog number :
MBS2520225
products type :
Antibody
products full name :
IFT140 Antibody
products short name :
[IFT140]
products name syn :
[DKFZp564L232; FLJ10306; FLJ30571; KIAA0590; WDTC2; c305C8.4; c380F5.1; gs114]
other names :
[intraflagellar transport protein 140 homolog; Intraflagellar transport protein 140 homolog; intraflagellar transport protein 140 homolog; WD and tetratricopeptide repeats protein 2; intraflagellar transport 140 homolog; intraflagellar transport 140; WD and tetratricopeptide repeats protein 2]
products gene name :
[IFT140]
other gene names :
[IFT140; IFT140; MZSDS; SRTD9; WDTC2; gs114; c305C8.4; c380F5.1; KIAA0590; WDTC2]
uniprot entry name :
IF140_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
1462
purity :
Antigen affinity purification
storage stability :
Store at -20 degree C. Avoid freeze / thaw cycles
tested application :
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
app notes :
WB: 1:200-1:2000. IF: 1:20-200
image1 heading :
Testing Data
other info1 :
Immunogen: Fusion protein of IFT140.
other info2 :
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
products description :
Component of the IFT complex A (IFT-A) a complex required for retrograde ciliary transport. PLays a pivotal role in proper development and function of ciliated cells. Involved in ciliogenesis and cilia maintenance.
ncbi gi num :
41281447
ncbi acc num :
NP_055529.2
ncbi gb acc num :
NM_014714.3
ncbi mol weight :
Calculated MW: 165kDa. Observed MW: 140kDa
ncbi pathways :
Assembly Of The Primary Cilium Pathway (1127502); Hedgehog 'off' State Pathway (1127538); Intraflagellar Transport Pathway (1127509); Organelle Biogenesis And Maintenance Pathway (1127494); Signal Transduction Pathway (477114); Signaling By Hedgehog Pathway (1127535)
ncbi summary :
This gene encodes one of the subunits of the intraflagellar transport (IFT) complex A. Intraflagellar transport is involved in the genesis, resorption and signaling of primary cilia. The primary cilium is a microtubule-based sensory organelle at the surface of most quiescent mammalian cells, that receives signals from its environment, such as the flow of fluid, light or odors, and transduces those signals to the nucleus. Loss of the corresponding protein in mouse results in renal cystic disease. [provided by RefSeq, Jun 2012]
uniprot summary :
IFT140: Plays a pivotal role in proper development and function of ciliated cells. Involved in ciliogenesis and cilia maintenance. Defects in IFT140 are the cause of Mainzer-Saldino syndrome (MZSDS). MZSDS is a rare autosomal recessive disease characterized by phalangeal cone- shaped epiphyses, chronic renal disease, nearly constant retinal dystrophy, and mild radiographic abnormality of the proximal femur. Occasional features include short stature, cerebellar ataxia, and hepatic fibrosis. Protein type: Adaptor/scaffold. Chromosomal Location of Human Ortholog: 16p13.3. Cellular Component: centrosome; axoneme; photoreceptor connecting cilium. Biological Process: skeletal morphogenesis; retina development in camera-type eye; organelle organization and biogenesis; cilium biogenesis. Disease: Short-rib Thoracic Dysplasia 9 With Or Without Polydactyly
size1 :
0.06 mL
price1 :
195 USD
size2 :
0.12 mL
price2 :
270
size3 :
0.2 mL
price3 :
435
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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