catalog number :
MBS2520086
products full name :
EXOC6 Antibody
products short name :
[EXOC6]
products name syn :
[DKFZp761I2124; EXOC6A; FLJ1125; FLJ11251; MGC33397; SEC15; SEC15L; SEC15L1; SEC15L3; Sec15p]
other names :
[Exocyst complex component 6; Exocyst complex component 6; exocyst complex component 6; SEC15-like 1; SEC15-like protein 1; SEC15-like protein 3; exocyst complex component Sec15A; exocyst complex component 6; Exocyst complex component Sec15A; SEC15-like protein 1]
products gene name :
[EXOC6]
other gene names :
[EXOC6; EXOC6; SEC15; EXOC6A; SEC15L; Sec15p; SEC15L1; SEC15L3; SEC15A; SEC15L; SEC15L1]
uniprot entry name :
EXOC6_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Antigen affinity purification
storage stability :
Store at -20 degree C. Avoid freeze / thaw cycles
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
WB: 1:500-1:5000
image1 heading :
Testing Data
other info1 :
Immunogen: Fusion protein of EXOC6. Calculated Molecular Weight: 804aa; 94kd. Observed Molecular Weight: 116kd
other info2 :
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-34366 / sc-34365 / sc-34367 / sc-67070
ncbi pathways :
Arf6 Trafficking Events Pathway (137954); Assembly Of The Primary Cilium Pathway (1127502); Cargo Trafficking To The Periciliary Membrane Pathway (1127504); Insulin Pathway (138026); Insulin Processing Pathway (105903); Membrane Trafficking Pathway (106160); Metabolism Of Proteins Pathway (106230); Organelle Biogenesis And Maintenance Pathway (1127494); Peptide Hormone Metabolism Pathway (771603); Translocation Of GLUT4 To The Plasma Membrane Pathway (685554)
ncbi summary :
The product of this gene belongs to the SEC15 family. It is highly similar to the protein encoded by Saccharomyces cerevisiae SEC15 gene. This protein is essential for vesicular traffic from the Golgi apparatus to the cell surface in yeast. It is one of the components of a multiprotein complex required for exocytosis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
uniprot summary :
EXOC6: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Together with RAB11A, RAB3IP, RAB8A, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. Belongs to the SEC15 family. Chromosomal Location of Human Ortholog: 10q23.33. Cellular Component: plasma membrane; exocyst; cytosol. Biological Process: protein transport; cellular protein metabolic process; organelle organization and biogenesis; erythrocyte differentiation; vesicle docking during exocytosis