product summary
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company name :
MyBioSource
product type :
antibody
product name :
CAMSAP2 Monoclonal Antibody
catalog :
MBS2519816
quantity :
0.06 mL
price :
220 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
[2A10A1]
reactivity :
human, mouse, rat
application :
western blot, ELISA, enzyme immunoassay
more info or order :
image
image 1 :
Western Blot analysis of HEK-293 cells using CAMSAP2 Monoclonal Antibody at dilution of 1:1000.
product information
catalog number :
MBS2519816
products type :
Antibody
products full name :
CAMSAP2 Monoclonal Antibody
products short name :
[CAMSAP2]
products name syn :
[CAMSAP1L1, CAMSAP2, KIAA1078]
other names :
[calmodulin-regulated spectrin-associated protein 2 isoform 1; Calmodulin-regulated spectrin-associated protein 2; calmodulin-regulated spectrin-associated protein 2; calmodulin regulated spectrin associated protein family member 2; Calmodulin-regulated spectrin-associated protein 1-like protein 1]
products gene name :
[CAMSAP2]
other gene names :
[CAMSAP2; CAMSAP2; CAMSAP1L1]
clonality :
Monoclonal
isotype :
IgG1
clone :
[2A10A1]
host :
Mouse
reactivity :
Human, Mouse, Rat
sequence length :
1489
purity :
Protein A purification
concentration :
1mg/mL
storage stability :
Store at -20 degree C. Avoid freeze / thaw cycles.
tested application :
Western Blot (WB), ELISA (EIA)
app notes :
WB: 1:500-1:2000
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: Fusion protein of CAMSAP2
other info2 :
Buffer: PBS with 0.1% sodium azide, 50% glycerol, PH7.3. Conjugation: Unconjugated
products categories :
Signal transduction
products description :
CAMSAP2, also known as CAMSAP1L1, is a microtubule minus-end binding protein, and is required for proper microtubule organization in neurons. CAMSAP2 stabilizes noncentrosomal microtubules and is important for neuronal polarity, axon specification, and dendritic branch formation.
ncbi gi num :
663071131
ncbi acc num :
NP_001284636.1
ncbi gb acc num :
NM_001297707.1
uniprot acc num :
Q08AD1
ncbi mol weight :
Calculated: 1478aa, 167kDa. Observed: 170-200kDa
uniprot summary :
Key microtubule-organizing protein that specifically binds the minus-end of non-centrosomal microtubules and regulates their dynamics and organization (PubMed:23169647, PubMed:24486153, PubMed:24706919). Specifically recognizes growing microtubule minus-ends and autonomously decorates and stabilizes microtubule lattice formed by microtubule minus-end polymerization (PubMed:24486153, PubMed:24706919). Acts on free microtubule minus-ends that are not capped by microtubule-nucleating proteins or other factors and protects microtubule minus-ends from depolymerization (PubMed:24486153, PubMed:24706919). In addition, it also reduces the velocity of microtubule polymerization (PubMed:24486153, PubMed:24706919). Through the microtubule cytoskeleton, also regulates the organization of cellular organelles including the Golgi and the early endosomes (PubMed:27666745). Essential for the tethering, but not for nucleation of non-centrosomal microtubules at the Golgi: together with Golgi-associated proteins AKAP9 and PDE4DIP, required to tether non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement (PubMed:27666745). Also acts as a regulator of neuronal polarity and development: localizes to non-centrosomal microtubule minus-ends in neurons and stabilizes non-centrosomal microtubules, which is required for neuronal polarity, axon specification and dendritic branch formation (PubMed:24908486). Through the microtubule cytoskeleton, regulates the autophagosome transport (PubMed:28726242).
size1 :
0.06 mL
price1 :
220 USD
size2 :
0.12 mL
price2 :
290
size3 :
0.2 mL
price3 :
435
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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