product summary
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company name :
MyBioSource
product type :
antibody
product name :
GPM6A Polyclonal Antibody
catalog :
MBS2519283
quantity :
0.02 mL
price :
110 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS2519283 image 1
Western Blot analysis of Human fetal brain tissue using GPM6A Polyclonal Antibody at dilution of 1:1050
image 2 :
MyBioSource MBS2519283 image 2
Immunohistochemistry of paraffin-embedded Human brain using GPM6A Polyclonal Antibody at dilution of 1:50
image 3 :
MyBioSource MBS2519283 image 3
Immunohistochemistry of paraffin-embedded Human thyroid cancer using GPM6A Polyclonal Antibody at dilution of 1:50
product information
catalog number :
MBS2519283
products type :
Antibody
products full name :
GPM6A Polyclonal Antibody
products short name :
[GPM6A]
products name syn :
[M6A; GPM6]
other names :
[GPM6A protein; Neuronal membrane glycoprotein M6-a; neuronal membrane glycoprotein M6-a; glycoprotein M6A]
products gene name :
[GPM6A]
other gene names :
[GPM6A; GPM6A; M6A; GPM6; M6A; M6a]
uniprot entry name :
GPM6A_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
78
sequence :
human GPM6A,at AA range: 148-278aa
purity :
Antigen affinity purification
concentration :
2.1mg/mL
storage stability :
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:1000-1:5000. IHC: 1:50-1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
products description :
Background/Introduction: Neuronal membrane glycoprotein M6-a is a protein that in humans is encoded by the GPM6A gene. Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.
ncbi gi num :
71296879
ncbi acc num :
AAH37853.1
ncbi mol weight :
31kDa
uniprot summary :
GPM6A: Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G- protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor. Belongs to the myelin proteolipid protein family. Protein type: Membrane protein, multi-pass; Channel, calcium; Membrane protein, integral; Cell surface. Chromosomal Location of Human Ortholog: 4q34. Cellular Component: neuron projection; cell soma; dendritic spine; integral to membrane; plasma membrane; vesicle; filopodium. Molecular Function: protein binding; calcium channel activity. Biological Process: positive regulation of filopodium formation; synaptogenesis; neuron migration; stem cell differentiation; neurite morphogenesis
size1 :
0.02 mL
price1 :
110 USD
size2 :
0.06 mL
price2 :
150
size3 :
0.12 mL
price3 :
225
size4 :
0.2 mL
price4 :
360
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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