catalog number :
MBS2518898
products full name :
CD5L Polyclonal Antibody
products short name :
[CD5L]
products name syn :
[AIM; API6; PRO229; Spalpha; SP-ALPHA]
other names :
[CD5 antigen-like; CD5 antigen-like; CD5 antigen-like; CD5 antigen-like (scavenger receptor cysteine rich family); CT-2; apoptosis inhibitor 6; igM-associated peptide; CD5 molecule-like; CT-2; IgM-associated peptide; SP-alpha]
products gene name :
[CD5L]
other gene names :
[CD5L; CD5L; AIM; API6; PRO229; Spalpha; SP-ALPHA; API6]
uniprot entry name :
CD5L_HUMAN
reactivity :
Human, Mouse
purity :
Antigen affinity purification
storage stability :
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
tested application :
ELISA (EIA), Immunohistochemistry (IHC)
app notes :
IHC: 1:50-1:200
image1 heading :
Immunohistochemistry (IHC)
image2 heading :
Immunohistochemistry (IHC)
products categories :
Cell biology
products description :
Background: CD5L (CD5 molecule-like), also known as API6, PRO229, Spalpha or SP-ALPHA, is a 347 amino acid secreted protein that belongs to the scavenger receptor cysteine-rich (SRCR) family of leukocyte regulating proteins. Expressed in bone marrow, spleen, thymus, lymph node and fetal liver, CD5L is thought to be involved in regulating the immune system via binding to peripheral monocytes and mediating their activation and overall survival. CD5L has three cysteine-rich domains and, in addition to its role in the immune system, may function to inhibit apoptosis and promote macrophage survival.
ncbi gb acc num :
NM_005894.2
uniprot summary :
CD5L: May play a role in the regulation of the immune system. Seems to play a role as an inhibitor of apoptosis. Protein type: Secreted, signal peptide; Receptor, misc.; Secreted. Chromosomal Location of Human Ortholog: 1q23.1. Cellular Component: extracellular space; membrane; extracellular region. Molecular Function: scavenger receptor activity. Biological Process: receptor-mediated endocytosis; apoptosis; cellular defense response