EDN2 Polyclonal Antibody | MyBioSource MBS2518418 product information

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company name :

MyBioSource

product type :

antibody

product name :

EDN2 Polyclonal Antibody

catalog :

MBS2518418

quantity :

0.02 mL

price :

110 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

image

image 1 :

Western Blot analysis of Human normal right lung and normal left lung tissue using EDN2 Polyclonal Antibody at dilution of 1:600

image 2 :

Immunohistochemistry of paraffin-embedded Human cervical cancer using EDN2 Polyclonal Antibody at dilution of 1:30

image 3 :

Immunohistochemistry of paraffin-embedded Human colon cancer using EDN2 Polyclonal Antibody at dilution of 1:30

product information

catalog number :

MBS2518418

products type :

Antibody

products full name :

EDN2 Polyclonal Antibody

products short name :

[EDN2]

products name syn :

[ET2; PPET2]

other names :

[endothelin-2 isoform 2 preproprotein; Endothelin-2; endothelin-2; preproendothelin 2; endothelin 2; Preproendothelin-2; PPET2]

products gene name :

[EDN2]

other gene names :

[EDN2; EDN2; ET2; ET-2; PPET2; ET-2; PPET2]

uniprot entry name :

EDN2_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human

sequence length :

145

purity :

Affinity purification

form :

PBS with 0.05% sodium azide, 50% glycerol, pH7.3

storage stability :

Store at -20 degree C. Avoid freeze / thaw cycles.

tested application :

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

app notes :

WB: 1:500-1:2000. IHC: 1:50-1:200

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

image3 heading :

Immunohistochemistry (IHC)

other info1 :

Immunogen: Recombinant protein of human EDN2

products description :

This gene encodes a member of the endothelin protein family of secretory vasoconstrictive peptides. The preproprotein is processed to a short mature form which functions as a ligand for the endothelin receptors that initiate intracellular signaling events. This gene product is involved in a wide range of biological processes, such as hypertension and ovulation.

ncbi gi num :

698980014

ncbi acc num :

NP_001289198.1

ncbi gb acc num :

NM_001302269.1

ncbi mol weight :

20kDa

ncbi pathways :

Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway (1127664); Direct P53 Effectors Pathway (137939); Disease Pathway (530764); Endothelins Pathway (137958); G Alpha (q) Signalling Events Pathway (106043); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Gastrin-CREB Signalling Pathway Via PKC And MAPK (645295); Metabolic Disorders Of Biological Oxidation Enzymes Pathway (1127637)

ncbi summary :

This gene encodes a member of the endothelin protein family of secretory vasoconstrictive peptides. The preproprotein is processed to a short mature form which functions as a ligand for the endothelin receptors that initiate intracellular signaling events. This gene product is involved in a wide range of biological processes, such as hypertension and ovulation. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

uniprot summary :

EDN2: Endothelins are endothelium-derived vasoconstrictor peptides. Belongs to the endothelin/sarafotoxin family. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 1p34. Cellular Component: extracellular space; extracellular region. Molecular Function: hormone activity. Biological Process: vasoconstriction; neutrophil chemotaxis; inositol phosphate-mediated signaling; regulation of systemic arterial blood pressure by endothelin; positive regulation of the force of heart contraction by chemical signal; cytokine and chemokine mediated signaling pathway; calcium-mediated signaling; positive regulation of leukocyte chemotaxis; positive regulation of heart rate; thermoregulation; prostaglandin biosynthetic process; vein smooth muscle contraction; hormonal regulation of the force of heart contraction; macrophage chemotaxis; macrophage activation; elevation of cytosolic calcium ion concentration; cell surface receptor linked signal transduction; regulation of vasoconstriction; positive regulation of cell proliferation; positive regulation of smooth muscle contraction; alveolus development; artery smooth muscle contraction

size1 :

0.02 mL

price1 :

110 USD

size2 :

0.06 mL

price2 :

150

size3 :

0.12 mL

price3 :

225

size4 :

0.2 mL

price4 :

360

more info or order :

MyBioSource product webpage