catalog number :
MBS2518067
products full name :
SLC6A7 Polyclonal Antibody
products short name :
[SLC6A7]
products name syn :
[PROT]
other names :
[sodium-dependent proline transporter; Sodium-dependent proline transporter; sodium-dependent proline transporter; brain-specific L-proline transporter; solute carrier family 6 (neurotransmitter transporter, L-proline), member 7; solute carrier family 6 member 7; solute carrier family 6 (neurotransmitter transporter), member 7; Solute carrier family 6 member 7]
products gene name :
[SLC6A7]
other gene names :
[SLC6A7; SLC6A7; PROT; PROT]
uniprot entry name :
SC6A7_HUMAN
purity :
Affinity purification
storage stability :
Store at -20 degree C. Avoid freeze / thaw cycles.
tested application :
ELISA (EIA), Immunohistochemistry (IHC)
app notes :
IHC: 1:25-1:100
image1 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Synthetic peptide of human SLC6A7
other info2 :
Buffer: PBS with 0.05% sodium azide, 50% glycerol, PH7.3. Note: Centrifuge before opening to ensure complete recovery of vial contents.
products description :
This gene is a member of the gamma-aminobutyric acid (GABA) neurotransmitter gene family and encodes a high-affinity mammalian brain L-proline transporter protein. This transporter protein differs from other sodium-dependent plasma membrane carriers by its pharmacological specificity, kinetic properties, and ionic requirements.
ncbi gb acc num :
NM_014228.3
ncbi pathways :
Creatine Metabolism Pathway (106192); Metabolism Pathway (477135); Metabolism Of Amino Acids And Derivatives Pathway (106169); Na+/Cl- Dependent Neurotransmitter Transporters Pathway (161070); SLC-mediated Transmembrane Transport Pathway (119558); Transmembrane Transport Of Small Molecules Pathway (106572); Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway (119571)
ncbi summary :
This gene is a member of the gamma-aminobutyric acid (GABA) neurotransmitter gene family and encodes a high-affinity mammalian brain L-proline transporter protein. This transporter protein differs from other sodium-dependent plasma membrane carriers by its pharmacological specificity, kinetic properties, and ionic requirements. [provided by RefSeq, Jul 2008]
uniprot summary :
SLC6A7: Terminates the action of proline by its high affinity sodium-dependent reuptake into presynaptic terminals. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A7 subfamily. Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter, SLC family; Transporter. Chromosomal Location of Human Ortholog: 5q32. Cellular Component: membrane; integral to plasma membrane; plasma membrane. Molecular Function: neurotransmitter:sodium symporter activity. Biological Process: transport; neurotransmitter transport; proline transport; transmembrane transport