catalog number :
MBS251801
products type :
Recombinant Protein
products full name :
Ceruloplasmin (CP)
products short name :
Ceruloplasmin (CP)
other names :
ceruloplasmin; Ceruloplasmin; ceruloplasmin; ceruloplasmin (ferroxidase); Ferroxidase
other gene names :
CP; CP; CP-2; N/A
uniprot entry name :
CERU_HUMAN
sequence :
The target protein is fused with N-terminal His-Tag, its sequence is listed below. DS TFRVPVERKA EEEHLGILGP QLHADVGDKV KIIFKNMATR PYSIHAHGVQ TESSTVTPTL PGETLTYVWK IPERSGAGTE DSACIPWAYY STVDQVKDLY SGLlGPLlVC RRPYLKVFNP RRKLEFALLF LVFDENESWY LDDNIKTYSD HPEKVNKDDE EFIESNKMHA INGRMFGNLQ GLTMHVGDEV NWYLMGMGNE IDLHTVHFHG HSFQYKHRGV YSSDVFDIFP GTYQTLEMFP RTPGIWLLHC HVTDHIHAGM ETTYTVLQNE DTKSG
form :
Supplied as lyophilized form in PBS, pH7.4, containing 1 mM OTT, 5% trehalose, 0.1 % sarcosyl and preservative.
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 Degree C for one month. Aliquot and store at -80 Degree C for 12 months. Stability Test: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 Degree C for 48h, and no obvious degradation and precipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
tested application :
SDS-PAGE; WB; ELISA; IP. (May be suitable for use in other assays to be determined by the end user.)
other info1 :
Tag Information: N-terminal His-Tag. Subcellular Location: Secreted. Endotoxin Level: 5.9. Predicted Molecular Mass: 33.0kDa. Usage: Reconstitute in sterile PBS, pH7.2-pH7.4.
other info2 :
Organism: Homo sapiens (Human)
ncbi acc num :
NP_000087.1
ncbi gb acc num :
NM_000096.3
ncbi mol weight :
122,205 Da
ncbi pathways :
HIF-1-alpha Transcription Factor Network Pathway 138045!!Iron Uptake And Transport Pathway 187191!!Metal Ion SLC Transporters Pathway 161066!!Porphyrin And Chlorophyll Metabolism Pathway 83021!!Porphyrin And Chlorophyll Metabolism Pathway 407!!SLC-mediated Transmembrane Transport Pathway 119558!!Transmembrane Transport Of Small Molecules Pathway 106572!!Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway 119571
ncbi summary :
The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II)transferrin to Fe(III) transferrin. Mutations in this gene cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Feb 2012]