product summary
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company name :
MyBioSource
product type :
antibody
product name :
AGGF1 Antibody
catalog :
MBS2517813
quantity :
0.06 mL
price :
195 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
image
image 1 :
Mouse liver tissue were subjected to SDS-PAGE followed by western blot with AGGF1 antibody at dilution 1:1000
image 2 :
Immunohistochemical of paraffin-embedded human spleen using AGGFI antibody at dilution of 1 :25 (under 40x lens)
product information
catalog number :
MBS2517813
products type :
Antibody
products full name :
AGGF1 Antibody
products short name :
[AGGF1]
products name syn :
[FLJ10283; GPATC7; GPATCH7; HSU84971]
other names :
[angiogenic factor with G patch and FHA domains 1; Angiogenic factor with G patch and FHA domains 1; angiogenic factor with G patch and FHA domains 1; G patch domain-containing protein 7; angiogenic factor VG5Q; vasculogenesis gene on 5q protein; angiogenic factor with G patch and FHA domains 1; Angiogenic factor VG5Q; hVG5Q; G patch domain-containing protein 7; Vasculogenesis gene on 5q protein]
products gene name :
[AGGF1]
other gene names :
[AGGF1; AGGF1; VG5Q; GPATC7; GPATCH7; HSU84971; HUS84971; GPATC7; GPATCH7; VG5Q; hVG5Q]
uniprot entry name :
AGGF1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
714
purity :
Antigen affinity purification
storage stability :
Store at -20 degree C. Avoid freeze / thaw cycles
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:500-1:5000. IHC: 1:20-1:200
image1 heading :
Testing Data
image2 heading :
Immunohistochemistry
other info1 :
Immunogen: Fusion protein of AGGF1. Calculated Molecular Weight: 714aa; 81kd. Observed Molecular Weight: 84-100 kDa
other info2 :
Buffer: PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-47569 / sc-47570 / sc-135246
products description :
The angiogenic factor gene, AGGF1 or (VG5Q), is identified as a candidate susceptibility gene for Klippel-Trenaunay syndrome (KTS) which is a severe congenital disorder characterized by capillary malformations, venous malformations or varicose veins, and hypertrophy of the afftected tissues. AGGF1 protein can bind to endothelial cells and promote cell proliferation. AGGF1 shows strong expression in blood vessels and is secreted as vessel formation is initiated. Regulation of AGGF1 by GATA1 may play roles in endothelial cell biology and angiogenesis.
ncbi gi num :
39725952
ncbi acc num :
NP_060516.2
ncbi gb acc num :
NM_018046.4
ncbi summary :
This gene encodes an angiogenic factor that promotes proliferation of endothelial cells. Mutations in this gene are associated with a susceptibility to Klippel-Trenaunay syndrome. Pseudogenes of this gene are found on chromosomes 3, 4, 10 and 16.[provided by RefSeq, Sep 2010]
uniprot summary :
AGGF1: Promotes angiogenesis and the proliferation of endothelial cells. Able to bind to endothelial cells and promote cell proliferation, suggesting that it may act in an autocrine fashion. Defects in AGGF1 are a cause of Klippel-Trenaunay syndrome (KTS). KTS is a congenital disease characterized by malformations of capillary (98% of KTS patients), venous (72%) and lymphatic (11%) vessels, and bony and soft tissue hypertrophy that leads to large cutaneous hemangiomata with hypertrophy of the related bones and soft tissues. 3 isoforms of the human protein are produced by alternative splicing. Protein type: RNA processing; Cell adhesion. Chromosomal Location of Human Ortholog: 5q13.3. Cellular Component: perinuclear region of cytoplasm; cytoplasm; extracellular region. Molecular Function: protein binding; nucleic acid binding. Biological Process: RNA processing; positive regulation of angiogenesis; positive regulation of endothelial cell proliferation; angiogenesis; cell adhesion; vasculogenesis. Disease: Klippel-trenaunay-weber Syndrome
size1 :
0.06 mL
price1 :
195 USD
size2 :
0.12 mL
price2 :
270
size3 :
0.2 mL
price3 :
435
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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