product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
CTSF Antibody
catalog :
MBS2517625
quantity :
0.06 mL
price :
195 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
image
image 1 :
Western Blot analysis of Human liver tissue , using Cathepsin F Polyclonal Antibody at dilution of 1:1000.
image 2 :
Immunohistochemistry of paraffin-embedded human prostate cancer using Cathepsin F Polyclonal Antibody at dilution of 1:100.
product information
catalog number :
MBS2517625
products type :
Antibody
products full name :
CTSF Antibody
products short name :
[CTSF]
products name syn :
[Cathepsin F, CATSF, CTSF]
other names :
[CTSF, partial; CTSF protein; cathepsin F; cathepsin F; CTSF protein]
products gene name :
[CTSF]
other gene names :
[CTSF; CTSF; CATSF; CLN13]
uniprot entry name :
Q6FHS1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
338
purity :
Affinity purification
storage stability :
Store at -20°C. Avoid freeze / thaw cycles
tested application :
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
app notes :
WB 1:500-1:2000. IHC 1:20-1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Fusion protein of Cathepsin F . Calculated MW: 53kd and 34kd. Buffer: PBS with 0.1% sodium azide, 50% glycerol, pH7.3
products description :
CTSF(Cathepsin F) is a member of the papain family of cysteine proteases. These enzymes represent a major component of the lysosomal proteolytic system. They are synthesized as inactive precursors consisting of a signal sequence, a propeptide, and a catalytically active mature region. Cathepsins are routed to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The deduced 484-amino acid cathepsin F protein has a signal sequence and potential glycosylation sites.
ncbi gi num :
49456321
ncbi acc num :
BC011682
uniprot acc num :
Q6FHS1
ncbi pathways :
Adaptive Immune System Pathway (366160); Immune System Pathway (106386); Lysosome Pathway (99052); Lysosome Pathway (96865); MHC Class II Antigen Presentation Pathway (645290)
ncbi summary :
Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF encodes a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W. [provided by RefSeq, Jul 2008]
uniprot summary :
CTSF: Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis. Belongs to the peptidase C1 family. Protein type: Protease; EC 3.4.22.41. Chromosomal Location of Human Ortholog: 11q13. Cellular Component: lysosomal lumen; lysosome; vesicle. Molecular Function: cysteine-type endopeptidase activity. Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; proteolysis. Disease: Ceroid Lipofuscinosis, Neuronal, 13
size1 :
0.06 mL
price1 :
195 USD
size2 :
0.12 mL
price2 :
270
size3 :
0.2 mL
price3 :
435
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!