product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
ITGAE Polyclonal Antibody
catalog :
MBS2517523
quantity :
0.02 mL
price :
110 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
image
image 1 :
Western Blot analysis of LoVo cell using ITGAE Polyclonal Antibody at dilution of 1:550
image 2 :
Immunohistochemistry of paraffin-embedded Human colon cancer using ITGAE Polyclonal Antibody at dilution of 1:50
image 3 :
Immunohistochemistry of paraffin-embedded Human ovarian cancer using ITGAE Polyclonal Antibody at dilution of 1:50
product information
catalog number :
MBS2517523
products type :
Antibody
products full name :
ITGAE Polyclonal Antibody
products short name :
[ITGAE]
products name syn :
[CD103; HUMINAE]
other names :
[Integrin alpha-E; Integrin alpha-E; integrin alpha-E; HML-1 antigen; antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide; integrin alpha-IEL; mucosal lymphocyte 1 antigen; integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide); HML-1 antigen; Integrin alpha-IEL; Mucosal lymphocyte 1 antigen; CD_antigen: CD103Cleaved into the following 2 chains:Integrin alpha-E light chain; Integrin alpha-E heavy chain]
products gene name :
[ITGAE]
other gene names :
[ITGAE; ITGAE; CD103; HUMINAE]
uniprot entry name :
ITAE_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
purity :
Affinity purification
concentration :
0.4mg/mL
storage stability :
Store at -20°C. Avoid freeze / thaw cycles.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:200-1:1000. IHC: 1:50-1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Recombinant protein of human ITGAE
other info2 :
Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3
products categories :
Stem cells
products description :
Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation.
ncbi gi num :
226694184
ncbi acc num :
BC113436
uniprot acc num :
P38570
ncbi mol weight :
130kDa
ncbi pathways :
E-cadherin Signaling In The Nascent Adherens Junction Pathway (138005); Extracellular Matrix Organization Pathway (576262); Focal Adhesion Pathway (198795); Integrin Cell Surface Interactions Pathway (106110); Integrin-mediated Cell Adhesion Pathway (198816); Regulation Of Actin Cytoskeleton Pathway (83089); Regulation Of Actin Cytoskeleton Pathway (500)
ncbi summary :
Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq, Jul 2008]
uniprot summary :
ITGAE: Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. Belongs to the integrin alpha chain family. Protein type: Motility/polarity/chemotaxis; Membrane protein, integral. Chromosomal Location of Human Ortholog: 17p13. Cellular Component: plasma membrane; integrin complex; external side of plasma membrane. Molecular Function: metal ion binding. Biological Process: integrin-mediated signaling pathway; extracellular matrix organization and biogenesis; cell adhesion
size1 :
0.02 mL
price1 :
110 USD
size2 :
0.06 mL
price2 :
150
size3 :
0.12 mL
price3 :
225
size4 :
0.2 mL
price4 :
360
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!
related products
browse more products
questions and comments