product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
IL22RA2 Polyclonal Antibody
catalog :
MBS2517441
quantity :
0.02 mL
price :
110 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS2517441 image 1
Western Blot analysis of SP20, Raji and 231 cell using IL22RA2 Polyclonal Antibody at dilution of 1:200
product information
catalog number :
MBS2517441
products type :
Antibody
products full name :
IL22RA2 Polyclonal Antibody
products short name :
[IL22RA2]
products name syn :
[CRF2X; CRF2-10; CRF2-S1; IL-22BP; IL-22RA2; ZCYTOR16; IL-22R-alpha-2]
other names :
[IL22RA2; Interleukin-22 receptor subunit alpha-2; interleukin-22 receptor subunit alpha-2; cytokine receptor class-II member 10; cytokine receptor family type 2, soluble 1; interleukin 22-binding protein; interleukin 22 receptor, alpha 2; Cytokine receptor class-II member 10; Cytokine receptor family 2 member 10; CRF2-10; Cytokine receptor family type 2, soluble 1; CRF2-S1; Interleukin-22-binding protein; IL-22BP; IL22BP; ZcytoR16]
products gene name :
[IL22RA2]
other gene names :
[IL22RA2; IL22RA2; CRF2X; CRF2-10; CRF2-S1; IL-22BP; IL-22RA2; ZCYTOR16; IL-22R-alpha-2; IL-22 receptor subunit alpha-2; IL-22R-alpha-2; IL-22RA2; CRF2-10; CRF2-S1; IL-22BP; IL22BP]
uniprot entry name :
I22R2_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
262
purity :
Antigen affinity purification
concentration :
0.5mg/mL
storage stability :
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
WB: 1:200-1:1000
image1 heading :
Western Blot (WB)
products description :
Background/Introduction: This gene encodes a member of the class II cytokine receptor family. The encoded soluble protein specifically binds to and inhibits interleukin 22 activity by blocking the interaction of interleukin 22 with its cell surface receptor. The encoded protein may be important in the regulation of inflammatory response, and has been implicated in the regulation of tumorigenesis in the colon. Alternative splicing results in multiple transcript variants encoding distinct isoforms.?
ncbi gi num :
37182593
ncbi acc num :
AAQ89097.1
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488)
ncbi summary :
This gene encodes a member of the class II cytokine receptor family. The encoded soluble protein specifically binds to and inhibits interleukin 22 activity by blocking the interaction of interleukin 22 with its cell surface receptor. The encoded protein may be important in the regulation of inflammatory response, and has been implicated in the regulation of tumorigenesis in the colon. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2013]
uniprot summary :
IL22RA2: Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses. Belongs to the type II cytokine receptor family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 6q23.3. Cellular Component: extracellular space; integral to membrane; plasma membrane; cytosol. Molecular Function: interleukin-22 binding; interleukin-22 receptor activity. Biological Process: regulation of tyrosine phosphorylation of Stat3 protein; negative regulation of inflammatory response; cytokine and chemokine mediated signaling pathway
size1 :
0.02 mL
price1 :
110 USD
size2 :
0.06 mL
price2 :
150
size3 :
0.12 mL
price3 :
225
size4 :
0.2 mL
price4 :
360
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!