catalog number :
MBS2517356
products full name :
ADAMTS16 Polyclonal Antibody
products short name :
[ADAMTS16]
products name syn :
[ADAMTS16s]
other names :
[A disintegrin and metalloproteinase with thrombospondin motifs 16 preproprotein; A disintegrin and metalloproteinase with thrombospondin motifs 16; A disintegrin and metalloproteinase with thrombospondin motifs 16; ADAM-TS 16; ADAM-TS16; ADAMTS-16; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 16; ADAM metallopeptidase with thrombospondin type 1 motif, 16]
products gene name :
[ADAMTS16]
other gene names :
[ADAMTS16; ADAMTS16; ADAMTS16s; KIAA2029; ADAM-TS 16; ADAM-TS16; ADAMTS-16]
uniprot entry name :
ATS16_HUMAN
reactivity :
Human, Mouse.
purity :
Affinity purification
storage stability :
Store at -20°C.Avoid freeze/thaw cycles.
tested application :
ELISA (EIA), Immunohistochemistry (IHC)
app notes :
IHC: 1:50-1:200
image1 heading :
Immunohistochemistry (IHC)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Synthetic peptide of human ADAMTS16
other info2 :
Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3
products categories :
Cell biology
products description :
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has high sequence similarity to the protein encoded by ADAMTS18, another family member.
ncbi acc num :
NP_620687.2
ncbi gb acc num :
NM_139056.2
ncbi pathways :
Degradation Of The Extracellular Matrix Pathway (576263); Extracellular Matrix Organization Pathway (576262); Metabolism Of Proteins Pathway (106230); O-glycosylation Of TSR Domain-containing Proteins Pathway (1127680); O-linked Glycosylation Pathway (1127679); Post-translational Protein Modification Pathway (161012)
ncbi summary :
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has high sequence similarity to the protein encoded by ADAMTS18, another family member. [provided by RefSeq, Jul 2008]
uniprot summary :
ADAMTS16: 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Protease; Motility/polarity/chemotaxis; EC 3.4.24.-; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 5p15. Cellular Component: proteinaceous extracellular matrix. Molecular Function: zinc ion binding; metalloendopeptidase activity. Biological Process: ureteric bud branching; proteolysis