product summary
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company name :
MyBioSource
product type :
antibody
product name :
PGLYRP1 Polyclonal Antibody
catalog :
MBS2517267
quantity :
0.02 mL
price :
110 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS2517267 image 1
Western Blot analysis of Hela and K562 cell, Human fetal liver tissue using PGLYRP1 Polyclonal Antibody at dilution of 1:200
product information
catalog number :
MBS2517267
products type :
Antibody
products full name :
PGLYRP1 Polyclonal Antibody
products short name :
[PGLYRP1]
products name syn :
[PGRP; TAG7; PGRPS; PGLYRP; PGRP-S; TNFSF3L]
other names :
[Peptidoglycan recognition protein 1; Peptidoglycan recognition protein 1; peptidoglycan recognition protein 1; TNF superfamily, member 3 (LTB)-like (peptidoglycan recognition protein); peptidoglycan recognition protein 1; Peptidoglycan recognition protein short; PGRP-S]
products gene name :
[PGLYRP1]
other gene names :
[PGLYRP1; PGLYRP1; PGRP; TAG7; PGRPS; PGLYRP; PGRP-S; TNFSF3L; PGLYRP; PGRP; TNFSF3L; PGRP-S]
uniprot entry name :
PGRP1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
196
purity :
Affinity purification
storage stability :
Store at -20°C. Avoid freeze/thaw cycles.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
WB: 1:200-1:1000
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: Synthetic peptide of human PGLYRP1. Calculated MW: 22kDa
other info2 :
Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3
products categories :
Cell biology
products description :
Peptidoglycan recognition proteins (PGRPs) are molecules that recognize peptidoglycan, a large component in bacterial cell walls. In insects, PGRPs activate antimicrobial pathways, and in mammals PGRPs function as antibacterial neutrophil proteins. PGRP-L halts bacterial growth by acting as an alanine amidase, an enzyme that hydrolyzes the amide bond of bacterial peptidoglycan. PGRP-Iå and PGRP-Ibeta are also members of the PGRP family that help recognize bacteria by binding to peptidoglycan and Gram-positive bacteria, but they do not have amidase activity. PGRP-S participates in intracellular killing of Gram-positive bacteria by stimulating two antimicrobial defense systems, the prophenoloxidase cascade and the antimicrobial peptides through Toll receptors.
ncbi gi num :
18202143
ncbi acc num :
O75594.1
uniprot summary :
PGLYRP1: Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. Protein type: Secreted, signal peptide; Apoptosis; Receptor, misc.; Secreted. Chromosomal Location of Human Ortholog: 19q13.2-q13.3. Cellular Component: extracellular region. Molecular Function: peptidoglycan receptor activity; peptidoglycan binding; zinc ion binding; N-acetylmuramoyl-L-alanine amidase activity. Biological Process: defense response to Gram-positive bacterium; negative regulation of natural killer cell differentiation during immune response; detection of bacterium; negative regulation of interferon-gamma production; negative regulation of inflammatory response; innate immune response; immune response; pattern recognition receptor signaling pathway; peptidoglycan catabolic process
size1 :
0.02 mL
price1 :
110 USD
size2 :
0.06 mL
price2 :
150
size3 :
0.12 mL
price3 :
225
size4 :
0.2 mL
price4 :
360
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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