product summary
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company name :
MyBioSource
product type :
antibody
product name :
CEP350-Specific Antibody
catalog :
MBS2517257
quantity :
0.06 mL
price :
195 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS2517257 image 1
Western Blot analysis of Mouse heart tissue, using CEP350-Specific Polyclonal Antibody at dilution of 1:600
image 2 :
MyBioSource MBS2517257 image 2
Immunohistochemistry of paraffin-embedded human testis slide using CEP350-Specific Polyclonal Antibody at dilution of 1:50
product information
catalog number :
MBS2517257
products type :
Antibody
products full name :
CEP350-Specific Antibody
products short name :
[CEP350-Specific]
products name syn :
[CAP350; FLJ38282; FLJ44058; GM133; KIAA0480]
other names :
[Centrosome-associated protein 350; Centrosome-associated protein 350; centrosome-associated protein 350; centrosomal protein 350kDa; Centrosome-associated protein of 350 kDa]
products gene name :
[CEP350]
other gene names :
[CEP350; CEP350; GM133; CAP350; CAP350; KIAA0480; Cep350]
uniprot entry name :
CE350_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
3117
purity :
Affinity purification
storage stability :
Store at -20 degree C. Avoid freeze / thaw cycles
tested application :
WB,IHC
app notes :
WB 1:500-1:1000, IHC 1:20-1:200
image1 heading :
Western Blot
image2 heading :
Immunohistochemistry
other info1 :
Immunogen: Peptide. Calculated Molecular Weight: 351kd. Observed Molecular Weight: 200-245kd; 143kd; 65kd
other info2 :
Buffer: PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
products description :
CEP350, also named as CAP350, FLJ38282, FLJ44058, GM133 and KIAA0480, plays an essential role in centriole growth by stabilizing a procentriolar seed composed of at least, SASS6 and CENPJ. It is required for anchoring microtubules to the centrosomes and for the integrity of the microtubule network. CEP350 recruits PPARA to discrete subcellular compartments and thereby modulates PPARA activity. The antibody is specific to CEP350.
ncbi gi num :
74746869
ncbi acc num :
Q5VT06.1
ncbi mol weight :
351 kDa
ncbi summary :
The product of this gene is a large protein with a CAP-Gly domain typically found in cytoskeleton-associated proteins. The encoded protein primarily localizes to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. The encoded protein directly interacts with another large centrosomal protein and is required to anchor microtubules at the centrosome. It is also implicated in the regulation of a class of nuclear hormone receptors in the nucleus. Several alternatively spliced transcript variants have been found, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
uniprot summary :
CEP350: Plays an essential role in centriole growth by stabilizing a procentriolar seed composed of at least, SASS6 and CENPJ. Required for anchoring microtubules to the centrosomes and for the integrity of the microtubule network. Recruits PPARA to discrete subcellular compartments and thereby modulates PPARA activity. Protein type: Nuclear receptor co-regulator; Cell cycle regulation. Chromosomal Location of Human Ortholog: 1q25.2. Cellular Component: nucleoplasm; centrosome; membrane; cytoplasm; spindle. Molecular Function: protein binding; microtubule binding
size1 :
0.06 mL
price1 :
195 USD
size2 :
0.12 mL
price2 :
270
size3 :
0.2 mL
price3 :
435
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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