product summary
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company name :
MyBioSource
product type :
antibody
product name :
CBLL1 Antibody
catalog :
MBS2517133
quantity :
0.06 mL
price :
195 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay
more info or order :
product information
catalog number :
MBS2517133
products type :
Antibody
products full name :
CBLL1 Antibody
products short name :
CBLL1
products name syn :
FLJ23109; HAKAI; MGC163401; MGC163403; RNF188
other names :
CBLL1 protein; E3 ubiquitin-protein ligase Hakai; E3 ubiquitin-protein ligase Hakai; Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1; Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1; E-cadherin binding protein E7; RING finger protein 188; c-Cbl-like protein 1; casitas B-lineage lymphoma-transforming sequence-like protein 1; Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase; Casitas B-lineage lymphoma-transforming sequence-like protein 1; RING finger protein 188; c-Cbl-like protein 1
products gene name :
CBLL1
other gene names :
CBLL1; CBLL1; HAKAI; RNF188; HAKAI; RNF188
uniprot entry name :
HAKAI_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
490
purity :
Antigen affinity purification
concentration :
1mg/mL
storage stability :
Store at -20 degree C. Avoid freeze / thaw cycles
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
WB: 1:500-1:5000. IHC: 1:20-1:200. IF: 1:20-1:50
other info1 :
Immunogen: CBLL1 fusion protein ag15463. Calculated Molecular Weight: 491aa; 55kd. Observed Molecular Weight: 56kd
other info2 :
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
ncbi gi num :
219518165
ncbi acc num :
AAI44177.1
ncbi mol weight :
54,390 Da
ncbi summary :
This gene encodes an E3 ubiquitin-ligase for the E-cadherin complex and mediates its ubiquitination, endocytosis, and degradation in the lysosomes. The encoded protein contains a RING-finger domain and is also thought to have a role in control of cell proliferation. A related pseudogene has been identified on chromosome X. Alternative splicing results in a non-coding transcript variant. [provided by RefSeq, Aug 2011]
uniprot summary :
CBLL1: Promotes ubiquitination of tyrosine-phosphorylated CDH1, thus targeting CDH1 for endocytosis and degradation. Protein type: EC 6.3.2.19; Ubiquitin ligase; Ubiquitin conjugating system; Cell adhesion; Motility/polarity/chemotaxis; C2H2-type zinc finger protein; Ligase; EC 6.3.2.-. Chromosomal Location of Human Ortholog: 7q22.3. Cellular Component: ubiquitin ligase complex. Molecular Function: identical protein binding; protein binding; zinc ion binding; ubiquitin-protein ligase activity; ligase activity. Biological Process: cell-cell adhesion; protein ubiquitination; positive regulation of endocytosis; negative regulation of cell adhesion; positive regulation of cell migration
size1 :
0.06 mL
price1 :
195 USD
size2 :
0.12 mL
price2 :
270
size3 :
0.2 mL
price3 :
435
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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