product summary
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company name :
MyBioSource
product type :
antibody
product name :
NCEH1 Polyclonal Antibody
catalog :
MBS2517098
quantity :
0.06 mL
price :
195 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2517098
products type :
Antibody
products full name :
NCEH1 Polyclonal Antibody
products short name :
NCEH1
products name syn :
NCEH; AADACL1
other names :
neutral cholesterol ester hydrolase 1 isoform c; Neutral cholesterol ester hydrolase 1; neutral cholesterol ester hydrolase 1; arylacetamide deacetylase-like 1; neutral cholesterol ester hydrolase 1; Arylacetamide deacetylase-like 1
products gene name :
NCEH1
other gene names :
NCEH1; NCEH1; NCEH; AADACL1; AADACL1; KIAA1363; NCEH
uniprot entry name :
NCEH1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
275
purity :
Antigen affinity purification
concentration :
2.7mg/mL
storage stability :
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:1000-1:5000. IHC: 1:100-1:300
other info1 :
Immunogen: Recombinant protein of human NCEH1. Calculated Molecular Weight: 46kDa
other info2 :
Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3
products description :
Neutral cholesterol ester hydrolase 1 (NCEH) also known as arylacetamide deacetylase-like 1 (AADACL1) or KIAA1363 is an enzyme that in humans is encoded by the NCEH1 gene. NCEH is an enzyme located in the endoplasmic reticulum. NCEH hydrolyzes 2-acetyl monoalkylglycerol ether, as part of an enzymatic pathway regulating the levels of platelet activating factor and lysophospholipids that may be involved in cancer development.
ncbi gi num :
226423952
ncbi acc num :
NP_001139750.1
ncbi gb acc num :
NM_001146278.1
ncbi pathways :
Bile Secretion Pathway (193146); Bile Secretion Pathway (193095)
uniprot summary :
AADACL1: a single-pass type II membrane microsomal protein. Hydrolyzes 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor (acetyl-glyceryl-ether-phosphorylcholine). Elevated in invasive cancer cells from several different tumor types. May be involved in the elevated neutral ether lipid content and elevated LPA signaling in cancer cells. May be responsible for cholesterol ester hydrolysis in macrophages, thereby contributing to the development of atherosclerosis. Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds. May contribute to cancer pathogenesis by promoting tumor cell migration. A key enzymatic node regulating an ether lipid signaling network in cancer; regulates MAGE and lysophospholipid levels in invasive cancer cells. Three alternatively spliced human isoforms have been described. Protein type: Hydrolase; Membrane protein, integral; EC 3.1.1.-. Chromosomal Location of Human Ortholog: 3q26.31. Cellular Component: membrane; endoplasmic reticulum; integral to membrane. Biological Process: lipid catabolic process
size1 :
0.06 mL
price1 :
195 USD
size2 :
0.12 mL
price2 :
270
size3 :
0.2 mL
price3 :
435
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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