product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
CAST Polyclonal Antibody
catalog :
MBS2516852
quantity :
0.02 mL
price :
110 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
image
image 1 :
Western Blot analysis of Lovo cell using CAST Polyclonal Antibody at dilution of 1:750
image 2 :
Immunohistochemistry of paraffin-embedded Human gastic cancer using CAST Polyclonal Antibody at dilution of 1:70
image 3 :
Immunohistochemistry of paraffin-embedded Human colon cancer using CAST Polyclonal Antibody at dilution of 1:70
product information
catalog number :
MBS2516852
products type :
Antibody
products full name :
CAST Polyclonal Antibody
products short name :
[CAST]
products name syn :
[BS-17]
other names :
[CAST protein, partial; Calpastatin; calpastatin; calpain inhibitor; sperm BS-17 component; calpastatin; Calpain inhibitor; Sperm BS-17 component]
products gene name :
[CAST]
other gene names :
[CAST; CAST; BS-17]
uniprot entry name :
ICAL_HUMAN
clonality :
polyclonal
isotype :
IgG
host :
rabbit
reactivity :
Human
purity :
Affinity purification
form :
PBS with 0.05% sodium azide, 50% glycerol, PH7.3
storage stability :
Store at -20°C. Avoid freeze / thaw cycles.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:500-1:2000. IHC: 1:100-1:300
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Recombinant protein of human CAST
products categories :
Cell biology; Neuroscience
products description :
The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.
ncbi gi num :
116284003
ncbi acc num :
BC013579
uniprot acc num :
P20810
ncbi mol weight :
77 kDa
ncbi summary :
The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]
uniprot summary :
calpastatin: Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue. Belongs to the protease inhibitor I27 (calpastatin) family. 7 isoforms of the human protein are produced by alternative splicing. Protein type: Inhibitor. Chromosomal Location of Human Ortholog: 5q15. Cellular Component: membrane; cytoplasm; cytosol. Molecular Function: protein binding; endopeptidase inhibitor activity; cysteine protease inhibitor activity. Disease: Peeling Skin With Leukonychia, Acral Punctate Keratoses, Cheilitis, And Knuckle Pads
size1 :
0.02 mL
price1 :
110 USD
size2 :
0.06 mL
price2 :
150
size3 :
0.12 mL
price3 :
225
size4 :
0.2 mL
price4 :
360
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!