product summary
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company name :
MyBioSource
product type :
antibody
product name :
AURKAIP1 Polyclonal Antibody
catalog :
MBS2516763
quantity :
0.02 mL
price :
110 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, enzyme immunoassay
more info or order :
image
image 1 :
MyBioSource MBS2516763 image 1
Western Blot analysis of Human testis tissue using AURKAIP1 Polyclonal Antibody at dilution of 1:600
product information
catalog number :
MBS2516763
products type :
Antibody
products full name :
AURKAIP1 Polyclonal Antibody
products short name :
[AURKAIP1]
products name syn :
[AIP; AKIP; MRP-S38]
other names :
[AURKAIP1 protein, partial; Aurora kinase A-interacting protein; aurora kinase A-interacting protein; 28S ribosomal protein S38, mitochondrial; AURKA-interacting protein; aurora-A kinase interacting protein; aurora kinase A interacting protein 1; 28S ribosomal protein S38, mitochondrial; MRP-S38]
products gene name :
[AURKAIP1]
other gene names :
[AURKAIP1; AURKAIP1; AIP; AKIP; MRP-S38; AIP; AKIP; MRPS38; AURKA-interacting protein; MRP-S38]
uniprot entry name :
AKIP_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
purity :
Affinity purification
form :
PBS with 0.05% sodium azide, 50% glycerol, pH 7.3
storage stability :
Store at -20°C. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB), ELISA (EIA)
app notes :
Western Blot: 1:500-1:2000
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: Recombinant protein of human AURKAIP1
other info2 :
Note: Centrifuge before opening to ensure complete recovery of vial contents.
products categories :
Cell biology
products description :
AKIP (AURKA-interacting protein), also known as AURKAIP1 (aurora kinase A interacting protein 1) or AIP, is a 199 amino acid protein that localizes to the nucleus and is ubiquitously expressed, with highest levels present in testis, heart and skeletal muscle. Interacting specifically with ARK-1 (aurora kinase 1), AKIP functions to induce the proteasomal-dependent degradation of ARK-1, thereby acting as a negative regulator of ARK-1 activity. AKIP is encoded by a gene which maps to human chromosome 1, which spans 260 million base pairs, contains over 3, 000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
ncbi gi num :
34783645
ncbi acc num :
BC062333
uniprot acc num :
Q9NWT8
ncbi mol weight :
22kDa
ncbi pathways :
Aurora A Signaling Pathway (137925); Mitochondrial Translation Pathway (1127498); Mitochondrial Translation Elongation Pathway (1127500); Mitochondrial Translation Initiation Pathway (1127499); Mitochondrial Translation Termination Pathway (1127501); Organelle Biogenesis And Maintenance Pathway (1127494)
uniprot summary :
AKIP: May act as a negative regulator of Aurora-A kinase, by down-regulation through proteasome-dependent degradation. Protein type: Cell cycle regulation. Chromosomal Location of Human Ortholog: 1p36.33. Cellular Component: nucleoplasm; mitochondrion; intracellular membrane-bound organelle; mitochondrial inner membrane; nucleus. Molecular Function: protein binding. Biological Process: mitochondrial translation; positive regulation of proteolysis; organelle organization and biogenesis; negative regulation of mitosis
size1 :
0.02 mL
price1 :
110 USD
size2 :
0.06 mL
price2 :
150
size3 :
0.12 mL
price3 :
225
size4 :
0.2 mL
price4 :
360
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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