catalog number :
MBS2516487
products full name :
CST7 Antibody
products short name :
[CST7]
products name syn :
[CMAP, CST7, Cystatin 7, Cystatin F, cystatin F (leukocystatin), Leukocystatin]
other names :
[cystatin-F; Cystatin-F; cystatin-F; cystatin-7; cystatin-like metastasis-associated protein; leukocystatin; cystatin F (leukocystatin); Cystatin-7; Cystatin-like metastasis-associated protein; CMAP; Leukocystatin]
products gene name :
[CST7]
other gene names :
[CST7; CST7; CMAP; CMAP]
uniprot entry name :
CYTF_HUMAN
reactivity :
Human, Mouse
purity :
Antigen affinity purification
form :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
storage stability :
Store at -20°C. Avoid freeze / thaw cycles
tested application :
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
app notes :
IHC 1:20-1:200. WB 1:500-1:1000
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Fusion protein of Cystatin F
products description :
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. This gene encodes a glycosylated cysteine protease inhibitor with a putative role in immune regulation through inhibition of a unique target in the hematopoietic system. Expression of the protein has been observed in various human cancer cell lines established from malignant tumors.
ncbi gb acc num :
NM_003650.3
ncbi mol weight :
Calculated: 167aa, 19 kDa . Observed: 19 kDa
ncbi summary :
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. This gene encodes a glycosylated cysteine protease inhibitor with a putative role in immune regulation through inhibition of a unique target in the hematopoietic system. Expression of the protein has been observed in various human cancer cell lines established from malignant tumors. [provided by RefSeq, Jul 2008]
uniprot summary :
CST7: Inhibits papain and cathepsin L but with affinities lower than other cystatins. May play a role in immune regulation through inhibition of a unique target in the hematopoietic system. Belongs to the cystatin family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 20p11.21. Cellular Component: cytoplasm; extracellular region. Molecular Function: protein binding; endopeptidase inhibitor activity; cysteine protease inhibitor activity. Biological Process: immune response