Human sFLT-1(Receptor for Vascular Endothelial cell Growth Factor VEGF)ELISA Kit | MyBioSource MBS2516240 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human sFLT-1(Receptor for Vascular Endothelial cell Growth Factor VEGF)ELISA Kit

catalog :

MBS2516240

quantity :

24-Strip-Wells

price :

215 USD

product information

catalog number :

MBS2516240

products type :

ELISA Kit

products full name :

Human sFLT-1(Receptor for Vascular Endothelial cell Growth Factor VEGF)ELISA Kit

products short name :

[sFLT-1]

other names :

[sFlt-1; Vascular endothelial growth factor receptor 1; vascular endothelial growth factor receptor 1; embryonic receptor kinase 2; tyrosine-protein kinase receptor FLT; vascular endothelial growth factor receptor-1; vascular permeability factor receptor; FMS-like tyrosine kinase 1; Embryonic receptor kinase 2; Fms-like tyrosine kinase 1; FLT-1; Tyrosine-protein kinase receptor FLT]

products gene name :

[sFLT-1]

other gene names :

[Flt1; Flt1; Flt-1; sFlt1; VEGFR1; VEGFR-1; AI323757; Emrk2; Flt; Vegfr1; VEGFR-1; FLT-1]

uniprot entry name :

VGFR1_MOUSE

reactivity :

Human

sequence length :

688

specificity :

This kit recognizes Human suPAR in samples. No significant cross-reactivity or interference between HumansuPARand analogues was observed.

storage stability :

Store at 4 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma And Other Biological Fluids. Assay Type: Quantitative Sandwich. Detection Range: 0.16-10ng/mL. Sensitivity: 0.1ng/mL.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): 3 samples with low, midrange and high level HumansuPAR were tested 20times on one plate, respectively. Inter-assay Precision: Inter-assay Precision (Precision between assays): 3 samples with low, midrange and high level HumansuPARwere testedon 3 different plates, 20 replicates in each plate.

products description :

Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Human suPAR concentrations in serum, plasma and other biological fluids. Principle of the Assay: This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human suPAR. Standards or samples are added to the micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Human suPAR and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human suPAR, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Human suPAR. You can calculate the concentration of Human suPAR in the samples by comparing the OD of the samples to the standard curve.

ncbi gi num :

2809071

ncbi acc num :

BAA24499.1

ncbi mol weight :

149,876 Da

ncbi pathways :

Cytokine-cytokine Receptor Interaction Pathway (83248); Cytokine-cytokine Receptor Interaction Pathway (460); Endocytosis Pathway (102286); Endocytosis Pathway (102181); Focal Adhesion Pathway (198353); Focal Adhesion Pathway (83264); Focal Adhesion Pathway (478); HIF-1 Signaling Pathway (695223); Id Signaling Pathway (198411); Neurophilin Interactions With VEGF And VEGFR Pathway (1110458)

uniprot summary :

VEGFR1: a receptor tyrosine kinase of the VEGFR family. Receptor for VEGF, VEGFB and PGF. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Two splice variant isoforms have been described. Isoform SFlt1 may have an inhibitory role in angiogenesis. Protein type: EC 2.7.10.1; Kinase, protein; Protein kinase, TK; Protein kinase, tyrosine (receptor); Membrane protein, integral; TK group; VEGFR family. Cellular Component: focal adhesion; membrane; integral to plasma membrane; integral to membrane; plasma membrane; receptor complex; endosome. Molecular Function: transferase activity; vascular endothelial growth factor receptor activity; identical protein binding; protein-tyrosine kinase activity; growth factor binding; transferase activity, transferring phosphorus-containing groups; nucleotide binding; transmembrane receptor protein tyrosine kinase activity; kinase activity; ATP binding; protein kinase activity. Biological Process: cell migration; peptidyl-tyrosine phosphorylation; multicellular organismal development; protein amino acid autophosphorylation; positive regulation of phosphoinositide 3-kinase activity; chemotaxis; protein amino acid phosphorylation; positive regulation of vascular endothelial growth factor receptor signaling pathway; positive regulation of phosphoinositide 3-kinase cascade; patterning of blood vessels; monocyte chemotaxis; positive regulation of MAP kinase activity; positive regulation of angiogenesis; positive regulation of MAPKKK cascade; response to hypoxia; blood vessel morphogenesis; angiogenesis; embryonic morphogenesis; sprouting angiogenesis; cell differentiation; vascular endothelial growth factor receptor signaling pathway; phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway; positive regulation of cell migration

size1 :

24-Strip-Wells

price1 :

215 USD

size2 :

48-Strip-Wells

price2 :

410

size3 :

96-Strip-Wells

price3 :

490

size4 :

5x96-Strip-Wells

price4 :

2040

size5 :

10x96-Strip-Wells

price5 :

3590