Mouse Nrf2(Nuclear factor erythroid 2-related factor 2)ELISA Kit | MyBioSource MBS2516218 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Nrf2(Nuclear factor erythroid 2-related factor 2)ELISA Kit

catalog :

MBS2516218

quantity :

24-Strip-Wells

price :

215 USD

more info or order :

MyBioSource product webpage

image

image 1 :

product information

catalog number :

MBS2516218

products type :

ELISA Kit

products full name :

Mouse Nrf2(Nuclear factor erythroid 2-related factor 2)ELISA Kit

products short name :

[Nrf2]

other names :

[nuclear factor erythroid 2-related factor 2 isoform 1; Nuclear factor erythroid 2-related factor 2; nuclear factor erythroid 2-related factor 2; HEBP1; NF-E2-related factor 2; NFE2-related factor 2; nuclear factor (erythroid-derived 2)-like 2; nuclear factor erythroid-derived 2-like 2; nuclear factor, erythroid derived 2, like 2; nuclear factor, erythroid 2-like 2; HEBP1; Nuclear factor, erythroid derived 2, like 2]

products gene name :

[Nrf2]

other gene names :

[NFE2L2; NFE2L2; NRF2; NRF2; NF-E2-related factor 2; NFE2-related factor 2]

uniprot entry name :

NF2L2_HUMAN

reactivity :

Mouse

sequence length :

605

specificity :

This kit recognizes Mouse NEO in samples. No significantcross-reactivity or interference between MouseNEO and analogues was observed.

storage stability :

Store at 4 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma And Other Biological Fluids. Assay Type: Quantitative Sandwich. Detection Range: 31.25-2000pg/mL. Sensitivity: 18.75pg/mL.

products description :

Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Mouse NEO concentrations in serum, plasma and other biological fluids. Principle of the Assay: This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Mouse NEO. Standards or samples are added to the micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Mouse NEO and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Mouse NEO, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Mouse NEO. You can calculate the concentration of Mouse NEO in the samples by comparing the OD of the samples to the standard curve.

ncbi gi num :

20149576

ncbi acc num :

NP_006155.2

ncbi gb acc num :

NM_006164.4

ncbi mol weight :

65,356 Da

ncbi pathways :

AhR Pathway (755436); Keap1-Nrf2 Pathway (198777); Oxidative Stress Pathway (198916); Protein Processing In Endoplasmic Reticulum Pathway (167325); Protein Processing In Endoplasmic Reticulum Pathway (167190); Selenium Metabolism And Selenoproteins Pathway (198846)

ncbi summary :

This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

uniprot summary :

NRF2: a transcription factor that regulates basal expression and antioxidant induction of a transcription factor for NAD(P)H:quinone oxidoreductase-1 (NQO1) and other detoxifying genes. Targeted for proteasomal degradation by INrf2. Oxidative stress causes its phosphorylation and release from INrf2. Protein type: DNA-binding; Transcription factor. Chromosomal Location of Human Ortholog: 2q31. Cellular Component: nucleoplasm; centrosome; cytoplasm; plasma membrane; chromatin; cytosol; nucleus. Molecular Function: protein domain specific binding; protein binding; DNA binding; transcription factor activity. Biological Process: transcription from RNA polymerase II promoter; proteasomal ubiquitin-dependent protein catabolic process; positive regulation of blood coagulation; unfolded protein response; regulation of embryonic development; proteasomal ubiquitin-independent protein catabolic process; protein ubiquitination; positive regulation of transcription from RNA polymerase II promoter

size1 :

24-Strip-Wells

price1 :

215 USD

size2 :

48-Strip-Wells

price2 :

410

size3 :

96-Strip-Wells

price3 :

490

size4 :

5x96-Strip-Wells

price4 :

2040

size5 :

10x96-Strip-Wells

price5 :

3590

more info or order :

MyBioSource product webpage