Rat MAG (Myelin Associated Glycoprotein) ELISA Kit | MyBioSource MBS2515999 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Rat MAG (Myelin Associated Glycoprotein) ELISA Kit

catalog :

MBS2515999

quantity :

24-Strip-Wells

price :

215 USD

more info or order :

MyBioSource product webpage

image

image 1 :

product information

catalog number :

MBS2515999

products type :

ELISA Kit

products full name :

Rat MAG (Myelin Associated Glycoprotein) ELISA Kit

products short name :

[MAG]

other names :

[myelin-associated glycoprotein isoform c; Myelin-associated glycoprotein; myelin-associated glycoprotein; sialic acid binding Ig-like lectin 4A; sialic acid-binding immunoglobulin-like lectin 4A; myelin associated glycoprotein; Siglec-4a]

products gene name :

[MAG]

other gene names :

[MAG; MAG; GMA; S-MAG; SIGLEC4A; SIGLEC-4A; GMA]

uniprot entry name :

MAG_HUMAN

reactivity :

Rat

sequence length :

601

specificity :

This kit recognizes natural and recombinantRatMAG. No significant cross-reactivity or interference between RatMAG and analogues was observed.

storage stability :

Store at 4 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 78.125-5000pg/mL. Sensitivity: Min: 46.875pg/mL; Max: 5000pg/mL

products description :

Intended Uses: This ELISA kit applies to the invitro quantitative determination of RatMAGconcentrations in serum, plasma and other biological fluids. Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to MAG. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for MAGand Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain MAG, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of MAG.You can calculate the concentration of MAGin the samples by comparing the OD of the samples to the standard curve.

ncbi gi num :

312836851

ncbi acc num :

NP_001186145.1

ncbi gb acc num :

NM_001199216.1

ncbi mol weight :

66,224 Da

ncbi pathways :

Axonal Growth Inhibition (RHOA Activation) Pathway (106454); Basigin Interactions Pathway (106065); Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Cell Surface Interactions At The Vascular Wall Pathway (106062); Glial Cell Differentiation Pathway (698758); Hemostasis Pathway (106028); Signal Transduction Pathway (477114); Signalling By NGF Pathway (106439); Spinal Cord Injury Pathway (739007)

ncbi summary :

The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2010]

uniprot summary :

MAG: Adhesion molecule in postnatal neural development that mediates sialic-acid dependent cell-cell interactions between neuronal and myelinating cells. Preferentially binds to alpha-2,3- linked sialic acid. Binds to RTN4R. Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Cell adhesion; Membrane protein, integral. Chromosomal Location of Human Ortholog: 19q13.1. Cellular Component: paranode region of axon; plasma membrane; integral to membrane. Molecular Function: carbohydrate binding. Biological Process: substantia nigra development; nerve growth factor receptor signaling pathway; negative regulation of axonogenesis; cell adhesion; regulation of axonogenesis; blood coagulation; leukocyte migration

size1 :

24-Strip-Wells

price1 :

215 USD

size2 :

48-Strip-Wells

price2 :

410

size3 :

96-Strip-Wells

price3 :

490

size4 :

5x96-Strip-Wells

price4 :

2040

size5 :

10x96-Strip-Wells

price5 :

3590

more info or order :

MyBioSource product webpage