Human NRP2 (Neuropilin 2) ELISA Kit | MyBioSource MBS2515921 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human NRP2 (Neuropilin 2) ELISA Kit

catalog :

MBS2515921

quantity :

24-Strip-Wells

price :

215 USD

product information

catalog number :

MBS2515921

products type :

ELISA Kit

products full name :

Human NRP2 (Neuropilin 2) ELISA Kit

products short name :

[NRP2]

other names :

[neuropilin-2 isoform 3; Neuropilin-2; neuropilin-2; neuropilin-2a(17); neuropilin-2a(22); neuropilin-2b(0); receptor for VEGF165 and semaphorins class3; vascular endothelial cell growth factor 165 receptor 2; neuropilin 2; Vascular endothelial cell growth factor 165 receptor 2]

products gene name :

[NRP2]

other gene names :

[NRP2; NRP2; NP2; NPN2; PRO2714; VEGF165R2; VEGF165R2]

uniprot entry name :

NRP2_HUMAN

reactivity :

Human

sequence length :

909

specificity :

This kit recognizes Human NRIP1 in samples. No significant cross-reactivity or interference between Human NRIP1 and analogues was observed.

storage stability :

Store at 4 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma And Other Biological Fluids. Assay Type: Quantitative Sandwich. Detection Range: 0.31-20ng/mL. Sensitivity: 0.19ng/mL.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): 3 samples with low, mid range and high level Human NRIP1 were tested 20 times on one plate, respectively. Inter-assay Precision: Inter-assay Precision (Precision between assays): 3 samples with low, mid range and high level Human NRIP1 were tested on 3 different plates, 20 replicates in each plate.

products description :

Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Human NRIP1 concentrations in serum, plasma and other biological fluids. Principle of the Assay: This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human NRIP1. Standards or samples are added to the micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Human NRIP1 and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human NRIP1, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Human NRIP1. You can calculate the concentration of Human NRIP1 in the samples by comparing the OD of the samples to the standard curve.

ncbi gi num :

41872572

ncbi acc num :

NP_958436.1

ncbi gb acc num :

NM_201279.1

ncbi mol weight :

62,458 Da

ncbi pathways :

Axon Guidance Pathway (105688); Developmental Biology Pathway (477129); L1CAM Interactions Pathway (161003); Neurophilin Interactions With VEGF And VEGFR Pathway (106509); NrCAM Interactions Pathway (161009); Signal Transduction Pathway (477114); Signaling By VEGF Pathway (106506); Signaling Events Mediated By VEGFR1 And VEGFR2 Pathway (137940); VEGFR1 Specific Signals Pathway (137924)

ncbi summary :

This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

uniprot summary :

NRP2: High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF. Heterodimer with NRP1. Binds PLXNB1. Belongs to the neuropilin family. 5 isoforms of the human protein are produced by alternative splicing. Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Receptor, misc. Chromosomal Location of Human Ortholog: 2q33.3. Cellular Component: membrane; integral to membrane; extracellular region; plasma membrane. Molecular Function: heparin binding; vascular endothelial growth factor receptor activity; semaphorin receptor activity; cytokine binding; metal ion binding; growth factor binding; receptor activity. Biological Process: axon extension involved in axon guidance; axon guidance; positive regulation of endothelial cell proliferation; nerve development; angiogenesis; cell adhesion; vascular endothelial growth factor receptor signaling pathway

size1 :

24-Strip-Wells

price1 :

215 USD

size2 :

48-Strip-Wells

price2 :

410

size3 :

96-Strip-Wells

price3 :

490

size4 :

5x96-Strip-Wells

price4 :

2040

size5 :

10x96-Strip-Wells

price5 :

3590