catalog number :
MBS2515920
products type :
ELISA Kit
products full name :
Human NPTX2 (Neuronal Pentraxin 2) ELISA Kit
products short name :
[NPTX2]
other names :
[neuronal pentraxin-2; Neuronal pentraxin-2; neuronal pentraxin-2; apexin; neuronal activity-regulated pentaxin; neuronal pentraxin II; Neuronal pentraxin II; NP-II]
products gene name :
[NPTX2]
other gene names :
[NPTX2; NPTX2; NP2; NARP; NP-II; NP2; NP-II]
uniprot entry name :
NPTX2_HUMAN
specificity :
This kit recognizes natural and recombinantHumanNPTX2. No significant cross-reactivity or interference between HumanNPTX2 and analogues was observed.
storage stability :
Store at 4 degree C.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 0.156-10ng/mL. Sensitivity: Min: 0.094ng/mL; Max: 10ng/mL
products description :
Intended Uses: This ELISA kit applies to the invitro quantitative determination of HumanNPTX2concentrations in serum, plasma and other biological fluids. Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to NPTX2. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for NPTX2and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain NPTX2, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of NPTX2.You can calculate the concentration of NPTX2in the samples by comparing the OD of the samples to the standard curve.
ncbi acc num :
NP_002514.1
ncbi gb acc num :
NM_002523.2
ncbi mol weight :
47,042 Da
ncbi summary :
This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq, Feb 2009]
uniprot summary :
NPTX2: Likely to play role in the modification of cellular properties that underlie long-term plasticity. Binds to agar matrix in a calcium-dependent manner. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 7q21.3-q22.1. Cellular Component: extracellular region. Molecular Function: metal ion binding; carbohydrate binding. Biological Process: synaptic transmission
size5 :
10x96-Strip-Wells