catalog number :
MBS2515654
products type :
ELISA Kit
products full name :
Human TACSTD2(Tumor-associated calcium signal transducer 2)ELISA Kit
products short name :
[TACSTD2]
other names :
[tumor-associated calcium signal transducer 2; Tumor-associated calcium signal transducer 2; tumor-associated calcium signal transducer 2; 40kD glycoprotein, identified by monoclonal antibody GA733; cell surface glycoprotein TROP2; cell surface glycoprotein Trop-2; epithelial glycoprotein-1; gastrointestinal tumor-associated antigen GA7331; membrane component chromosome 1 surface marker 1; membrane component, chromosome 1, surface marker 1; pancreatic carcinoma marker protein GA733-1; pancreatic carcinoma marker protein GA7331; tumor-associated calcium signal transducer 2; Cell surface glycoprotein Trop-2; Membrane component chromosome 1 surface marker 1; Pancreatic carcinoma marker protein GA733-1]
products gene name :
[TACSTD2]
other gene names :
[TACSTD2; TACSTD2; EGP1; GP50; M1S1; EGP-1; TROP2; GA7331; GA733-1; GA733-1; M1S1; TROP2]
uniprot entry name :
TACD2_HUMAN
specificity :
This kit recognizes natural and some recombinant Human TACSTD2. No significant crossreactivity or interference between Human TACSTD2 and analogues was observed.
storage stability :
Store at 4 degree C.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 7.813-500pg/mL. Sensitivity: Min: 4.688pg/mL; Max: 500pg/mL
products description :
Intended Uses: This ELISA kit can be applied to the in vitro quantitative determination of Human TACSTD2 concentrations in serum, plasma and other biological fluids. Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been precoated with an antibody specific to Human TACSTD2. Standards or samples are added to appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibodies specific for Human TACSTD2 and Avidin-Horseradish Peroxidase (HRP) conjugate are added to each micro plate well successively and incubated. After incubation, free components are washed away. Then the Substrate Reagent is added to each well, only those wells that contain Human TACSTD2, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction will be terminated by adding Stop Solution and appears yellow in color. The optical density (OD) can be measured with spectrophotometry at a wavelength of 450 nm ± 2 nm. The OD value is proportional to the concentration of Human TACSTD2. The concentration of Human TACSTD2 in samples can be calculated by comparing the OD of the samples with the standard curve.
ncbi acc num :
NP_002344.2
ncbi gb acc num :
NM_002353.2
ncbi mol weight :
35,709 Da
ncbi summary :
This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.[provided by RefSeq, Dec 2009]
uniprot summary :
TACSTD2: May function as a growth factor receptor. Defects in TACSTD2 are the cause of gelatinous drop-like corneal dystrophy (GDLD); also known as lattice corneal dystrophy type III. GDLD is an autosomal recessive disorder characterized by grayish corneal amyloid deposits that cause severe visual impairment. Belongs to the EPCAM family. Protein type: Receptor, misc.; Membrane protein, integral. Chromosomal Location of Human Ortholog: 1p32. Cellular Component: extracellular space; membrane; integral to plasma membrane; basal plasma membrane; cytosol; nucleus; lateral plasma membrane. Molecular Function: protein binding; receptor activity. Biological Process: cell proliferation; cell surface receptor linked signal transduction; negative regulation of stress fiber formation; visual perception; regulation of epithelial cell proliferation. Disease: Corneal Dystrophy, Gelatinous Drop-like
size5 :
10x96-Strip-Wells