Rat ANGPTL3 (Angiopoietin Like Protein 3) ELISA Kit | MyBioSource MBS2515631 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Rat ANGPTL3 (Angiopoietin Like Protein 3) ELISA Kit

catalog :

MBS2515631

quantity :

24-Strip-Wells

price :

215 USD

product information

catalog number :

MBS2515631

products type :

ELISA Kit

products full name :

Rat ANGPTL3 (Angiopoietin Like Protein 3) ELISA Kit

products short name :

[ANGPTL3]

other names :

[angiopoietin-related protein 3 preproprotein; Angiopoietin-related protein 3; angiopoietin-related protein 3; angiopoietin 5; angiopoietin-like 3; Angiopoietin-5; ANG-5; Angiopoietin-like protein 3]

products gene name :

[ANGPTL3]

other gene names :

[ANGPTL3; ANGPTL3; ANL3; ANG-5; FHBL2; ANGPT5; ANGPT5; ANG-5]

uniprot entry name :

ANGL3_HUMAN

reactivity :

Rat

sequence length :

460

specificity :

This kit recognizes Rat Ang-II in samples. No significant cross-reactivity or interference between Rat Ang-II and analogues was observed.

storage stability :

Store at 4 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma And Other Biological Fluids. Assay Type: Quantitative Competitive. Detection Range: 15.63-1000 pg/mL. Sensitivity: 9.38pg/mL.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): 3 samples with low, midrange and high level Rat Ang-II were tested 20times on one plate, respectively. Inter-assay Precision: Inter-assay Precision (Precision between assays): 3 samples with low, midrange and high level Rat Ang-II were testedon 3 different plates, 20 replicates in each plate.

products description :

Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Rat ANG II concentrations in serum, plasma and other biological fluids. Principle of the Assay: This ELISA kit uses Competitive-ELISA as the method. The microtiter plate provided in this kit has been pre-coated with ANG II. During the reaction, ANG II in the sample or standard competes with a fixed amount of ANG II on the solid phase supporter for sites on the Biotinylated Detection Ab specific to ANG II. Excess conjugate and unbound sample or standard are washed from the plate, and Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of ANG II in the samples is then determined by comparing the OD of the samples to the standard curve.

ncbi gi num :

7656888

ncbi acc num :

NP_055310.1

ncbi gb acc num :

NM_014495.3

ncbi mol weight :

53,637 Da

ncbi pathways :

Integrins In Angiogenesis Pathway (137999)

ncbi summary :

This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metablism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2. [provided by RefSeq, Feb 2013]

uniprot summary :

ANGPTL3: Defects in ANGPTL3 are the cause of familial hypobetalipoproteinemia type 2 (FHBL2); also called combined hypobetalipoproteinemia familial. FHBL2 is a disorder of lipid metabolism characterized by less than 5th percentile age- and sex-specific levels of low density lipoproteins, and dietary fat malabsorption. Affected individuals present with combined hypolipidemia, consisting of extremely low plasma levels of LDL cholesterol, HDL cholesterol, and triglycerides. Protein type: Cell adhesion; Inhibitor; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 1p31.3. Cellular Component: extracellular space; cell surface. Molecular Function: integrin binding; enzyme inhibitor activity; phospholipase inhibitor activity; growth factor activity. Biological Process: integrin-mediated signaling pathway; cholesterol metabolic process; glycerol metabolic process; phospholipid catabolic process; cell-matrix adhesion; lipid homeostasis; positive regulation of lipid catabolic process; signal transduction; fatty acid metabolic process; sequestering of lipid; cholesterol homeostasis; positive regulation of angiogenesis; acylglycerol homeostasis; phospholipid metabolic process; artery morphogenesis; negative regulation of lipoprotein lipase activity; phospholipid homeostasis; positive regulation of cell migration. Disease: Hypobetalipoproteinemia, Familial, 2

size1 :

24-Strip-Wells

price1 :

215 USD

size2 :

48-Strip-Wells

price2 :

410

size3 :

96-Strip-Wells

price3 :

490

size4 :

5x96-Strip-Wells

price4 :

2040

size5 :

10x96-Strip-Wells

price5 :

3590