ELISA/assay

Human STC2 (Stanniocalcin 2) ELISA Kit

MBS2515626

24-Strip-Wells

215 USD

ELISA Kit

Human STC2 (Stanniocalcin 2) ELISA Kit

[STC2]

[stanniocalcin-2; Stanniocalcin-2; stanniocalcin-2; STC-related protein; stanniocalcin-related protein; stanniocalcin 2; Stanniocalcin-related protein; STC-related protein; STCRP]

[STC2]

[STC2; STC2; STC-2; STCRP; STC-2; STC-related protein; STCRP]

STC2_HUMAN

Human

302

This kit recognizes natural and some recombinant Human STC2. No significant crossreactivity or interference between Human STC2 and analogues was observed.

Store at 4 degree C.

Typical Testing Data/Standard Curve (for reference only)

Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 31.25-2000pg/mL. Sensitivity: Min: 18.75pg/mL; Max: 2000pg/mL

Intended Uses: This ELISA kit can be applied to the in vitro quantitative determination of Human STC2 concentrations in serum, plasma and other biological fluids. Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been precoated with an antibody specific to Human STC2. Standards or samples are added to appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibodies specific for Human STC2 and Avidin-Horseradish Peroxidase (HRP) conjugate are added to each micro plate well successively and incubated. After incubation, free components are washed away. Then the Substrate Reagent is added to each well, only those wells that contain Human STC2, biotinylated detection antibody and Avidin- HRP conjugate will appear blue in color. The enzyme-substrate reaction will be terminated by adding Stop Solution and appears yellow in color. The optical density (OD) can be measured with spectrophotometry at a wavelength of 450 nm ± 2 nm. The OD value is proportional to the concentration of Human STC2. The concentration of Human STC2 in samples can be calculated by comparing the OD of the samples with the standard curve.

4507267

NP_003705.1

NM_003714.2

33,249 Da

This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers. [provided by RefSeq, Jul 2008]

STC2: a secreted protein that has an anti-hypocalcemic action on calcium and phosphate homeostasis. Expressed in a variety of tissues including muscle, heart, pancreas, kidney, spleen, prostate, small intestine, colon and peripheral blood leucocytes. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 5q35.1. Cellular Component: Golgi apparatus; extracellular space; perinuclear region of cytoplasm; endoplasmic reticulum. Molecular Function: enzyme binding; protein homodimerization activity; hormone activity; heme binding. Biological Process: cellular calcium ion homeostasis; response to peptide hormone stimulus; negative regulation of multicellular organism growth; response to vitamin D; unfolded protein response; response to oxidative stress; decidualization; regulation of hormone biosynthetic process; embryo implantation

24-Strip-Wells

215 USD

48-Strip-Wells

410

96-Strip-Wells

490

5x96-Strip-Wells

2040

10x96-Strip-Wells

3590