This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
ELISA/assay
product name :
Rabbit BMP-2 (Bone Morphogenetic Protein 2) ELISA Kit
catalog :
MBS2514367
quantity :
24-Strip-Wells
price :
210 USD
product information
catalog number :
MBS2514367
products type :
ELISA Kit
products full name :
Rabbit BMP-2 (Bone Morphogenetic Protein 2) ELISA Kit
products short name :
[BMP-2]
other names :
[bone morphogenetic protein 2; Bone morphogenetic protein 2; bone morphogenetic protein 2; BMP-2A; bone morphogenetic protein 2A; bone morphogenetic protein 2; Bone morphogenetic protein 2A; BMP-2A]
products gene name :
[BMP-2]
other gene names :
[BMP2; BMP2; BDA2; BMP2A; BMP2A; BMP-2; BMP-2A]
uniprot entry name :
BMP2_HUMAN
reactivity :
Rabbit
sequence length :
396
specificity :
This kit recognizes natural and recombinant Rabbit BMP-2. No significant cross-reactivity or interference between Rabbit BMP-2 and analogues was observed.
storage stability :
Store at 4 degree C.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 31.25-2000pg/mL. Sensitivity: Min: 18.75pg/mL; Max: 2000pg/mL
other info2 :
Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Rabbit BMP-2 concentrations in serum, plasma and other biological fluids.
products description :
. Principle of the assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to BMP-2. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for BMP-2 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain BMP-2, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of BMP-2. You can calculate the concentration of BMP-2 in the samples by comparing the OD of the samples to the standard curve.
ncbi gi num :
6649952
ncbi acc num :
AAF21646.1
uniprot acc num :
P12643
ncbi mol weight :
44,702 Da
ncbi pathways :
Adipogenesis Pathway (198832); BDNF Signaling Pathway (712093); BMP Signaling Pathway (1084755); BMP Signaling Pathway (1108218); BMP Signalling And Regulation Pathway (198910); Basal Cell Carcinoma Pathway (83113); Basal Cell Carcinoma Pathway (525); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Elastic Fibre Formation Pathway (730310)
ncbi summary :
The protein encoded by this gene belongs to the transforming growth factor-beta (TGFB) superfamily. The encoded protein acts as a disulfide-linked homodimer and induces bone and cartilage formation. [provided by RefSeq, Jul 2008]
uniprot summary :
Induces cartilage and bone formation (PubMed:3201241). Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4 (PubMed:24362451).
size1 :
24-Strip-Wells
price1 :
210 USD
size2 :
48-Strip-Wells
price2 :
400
size3 :
96-Strip-Wells
price3 :
475
size4 :
5x96-Strip-Wells
price4 :
1975
size5 :
10x96-Strip-Wells
price5 :
3480
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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