Monkey FGF19 (Fibroblast Growth Factor 19) ELISA Kit | MyBioSource MBS2513928 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Monkey FGF19 (Fibroblast Growth Factor 19) ELISA Kit

catalog :

MBS2513928

quantity :

24-Strip-Wells

price :

235 USD

product information

catalog number :

MBS2513928

products type :

ELISA Kit

products full name :

Monkey FGF19 (Fibroblast Growth Factor 19) ELISA Kit

products short name :

[FGF19]

other names :

[fibroblast growth factor 19; Fibroblast growth factor 19; fibroblast growth factor 19; FGF-19; fibroblast growth factor 19]

products gene name :

[FGF19]

other gene names :

[FGF19; FGF19; FGF-19]

uniprot entry name :

FGF19_HUMAN

reactivity :

Monkey

sequence length :

216

specificity :

This kit recognizes Monkey ENA-78 in samples. No significant cross-reactivity or interference between Monkey ENA-78 and analogues was observed.

storage stability :

Store at 4 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma And Other Biological Fluids. Assay Type: Quantitative Sandwich. Detection Range: 31.25-2000pg/mL. Sensitivity: 18.75pg/mL

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): 3 samples with low, mid range and high level Monkey ENA-78 were tested 20 times on one plate, respectively. Inter-assay Precision: Inter-assay Precision (Precision between assays): 3 samples with low, mid range and high level Monkey ENA-78 were tested on 3 different plates, 20 replicates in each plate.

products description :

Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Monkey ENA-78 concentrations in serum, plasma and other biological fluids. Principle of the Assay: This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Monkey ENA-78. Standards or samples are added to the micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Monkey ENA-78 and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Monkey ENA-78, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Monkey ENA-78. You can calculate the concentration of Monkey ENA-78 in the samples by comparing the OD of the samples to the standard curve.

ncbi gi num :

4826726

ncbi acc num :

NP_005108.1

ncbi gb acc num :

NM_005117.2

uniprot acc num :

O95750

ncbi mol weight :

24,003 Da

ncbi pathways :

Adaptive Immune System Pathway (366160); Constitutive PI3K/AKT Signaling In Cancer Pathway (685535); DAP12 Interactions Pathway (685549); DAP12 Signaling Pathway (685550); Disease Pathway (530764); Downstream Signal Transduction Pathway (106385); Downstream Signaling Events Of B Cell Receptor (BCR) Pathway (576250); Downstream Signaling Of Activated FGFR Pathway (160957); FGF Signaling Pathway (137989); FGFR Ligand Binding And Activation Pathway (106344)

ncbi summary :

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This growth factor is a high affinity, heparin dependent ligand for FGFR4. Expression of this gene was detected only in fetal but not adult brain tissue. Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development. [provided by RefSeq, Jul 2008]

uniprot summary :

FGF19: Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4. Belongs to the heparin-binding growth factors family. Protein type: Cytokine; Motility/polarity/chemotaxis; Cell development/differentiation; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 11q13.1. Cellular Component: extracellular region. Molecular Function: protein binding; growth factor activity; fibroblast growth factor receptor binding. Biological Process: epidermal growth factor receptor signaling pathway; nervous system development; positive regulation of glucose import; phosphoinositide-mediated signaling; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; heart development; positive regulation of cell proliferation; insulin receptor signaling pathway; positive regulation of JNK cascade; innate immune response; positive regulation of protein amino acid phosphorylation; neural crest cell migration

size1 :

24-Strip-Wells

price1 :

235 USD

size2 :

48-Strip-Wells

price2 :

450

size3 :

96-Strip-Wells

price3 :

535

size4 :

5x96-Strip-Wells

price4 :

2255

size5 :

10x96-Strip-Wells

price5 :

3975