Mouse TRAIL R4 (Tumor Necrosis Factor-related Apoptosis-inducing Ligand 4) ELISA Kit | MyBioSource MBS2513902 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse TRAIL R4 (Tumor Necrosis Factor-related Apoptosis-inducing Ligand 4) ELISA Kit

catalog :

MBS2513902

quantity :

24-Strip-Wells

price :

215 USD

product information

catalog number :

MBS2513902

products type :

ELISA Kit

products full name :

Mouse TRAIL R4 (Tumor Necrosis Factor-related Apoptosis-inducing Ligand 4) ELISA Kit

products short name :

[TRAIL R4]

other names :

[tumor necrosis factor receptor superfamily member 10D; Tumor necrosis factor receptor superfamily member 10D; tumor necrosis factor receptor superfamily member 10D; TNF receptor-related receptor for TRAIL; TNF-related apoptosis-inducing ligand receptor 4; TRAIL receptor 4; TRAIL receptor with a truncated death domain; decoy receptor 2; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain; Decoy receptor 2; DcR2; TNF-related apoptosis-inducing ligand receptor 4; TRAIL receptor 4; TRAIL-R4; TRAIL receptor with a truncated death domain; CD_antigen: CD264]

products gene name :

[TRAIL-R4]

other gene names :

[TNFRSF10D; TNFRSF10D; DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4; DCR2; TRAILR4; TRUNDD; DcR2; TRAIL receptor 4; TRAIL-R4]

uniprot entry name :

TR10D_HUMAN

reactivity :

Mouse

sequence length :

386

specificity :

This kit recognizes Mouse TNNI3/cTn-I in samples. No significant cross-reactivity or interference between Mouse TNNI3/cTn-I and analogues was observed.

storage stability :

Store at 4 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma And Other Biological Fluids. Assay Type: Quantitative Sandwich. Detection Range: 7.81-500pg/mL. Sensitivity: 4.69pg/mL.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): 3 samples with low, midrange and high level MouseTNNI3/cTn-I were tested 20times on one plate, respectively. Inter-assay Precision: Inter-assay Precision (Precision between assays): 3 samples with low, midrange and high level MouseTNNI3/cTn-I were testedon 3 different plates, 20 replicates in eachplate

products description :

Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Mouse TNNI3/cTn-I concentrations in serum, plasma and other biological fluids. Principle of the Assay: This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Mouse TNNI3/cTn-I. Standards or samples are added to the micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Mouse TNNI3/cTn-I and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Mouse TNNI3/cTn-I, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Mouse TNNI3/cTn-I. You can calculate the concentration of Mouse TNNI3/cTn-I in the samples by comparing the OD of the samples to the standard curve.

ncbi gi num :

22547108

ncbi acc num :

NP_003831.2

ncbi gb acc num :

NM_003840.4

uniprot acc num :

Q9UBN6

ncbi mol weight :

41,823 Da

ncbi pathways :

Apoptosis Pathway (83060); Apoptosis Pathway (470); Apoptosis Modulation And Signaling Pathway (198822); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Direct P53 Effectors Pathway (137939); Influenza A Pathway (217173); Influenza A Pathway (217150); Measles Pathway (213306); Measles Pathway (213277)

ncbi summary :

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis. [provided by RefSeq, Jul 2008]

uniprot summary :

TRAIL-R4: Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF- kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway. Widely expressed, in particular in fetal kidney, lung and liver, and in adult testis and liver. Also expressed in peripheral blood leukocytes, colon and small intestine, ovary, prostate, thymus, spleen, pancreas, kidney, lung, placenta and heart. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 8p21. Cellular Component: integral to membrane. Molecular Function: transmembrane receptor activity; TRAIL binding. Biological Process: apoptosis; signal transduction; negative regulation of apoptosis

size1 :

24-Strip-Wells

price1 :

215 USD

size2 :

48-Strip-Wells

price2 :

410

size3 :

96-Strip-Wells

price3 :

490

size4 :

5x96-Strip-Wells

price4 :

2040

size5 :

10x96-Strip-Wells

price5 :

3590