This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
ELISA/assay
product name :
Mouse ANG2 (Angiopoietin 2) ELISA Kit
catalog :
MBS2513565
quantity :
24-Strip-Wells
price :
190 USD
product information
catalog number :
MBS2513565
products type :
ELISA Kit
products full name :
Mouse ANG2 (Angiopoietin 2) ELISA Kit
products short name :
[ANG2]
other names :
[angiopoietin-2 isoform c; Angiopoietin-2; angiopoietin-2; ANG-2; Tie2-ligand; angiopoietin-2B; angiopoietin-2a; angiopoietin 2]
products gene name :
[ANG2]
other gene names :
[ANGPT2; ANGPT2; ANG2; AGPT2; ANG-2]
uniprot entry name :
ANGP2_HUMAN
reactivity :
Mouse
sequence length :
444
specificity :
This kit recognizes natural and some recombinant Mouse ANG2. No significant crossreactivity or interference between Mouse ANG2 and analogues was observed.
storage stability :
Store at 4 degree C.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 31.25-2000pg/mL. Sensitivity: Min: 18.75pg/mL; Max: 2000pg/mL
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level Mouse ANG2 were tested 20 times on one plate, respectively. Inter-assay Precision: Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level Mouse ANG2 were tested on 3 different plates, 20 replicates in each plate.
products description :
Intended Uses: This ELISA kit can be applied to the in vitro quantitative determination of Mouse ANG2 concentrations in serum, plasma and other biological fluids.
ncbi gi num :
169646754
ncbi acc num :
NP_001112360.1
ncbi gb acc num :
NM_001118888.1
uniprot acc num :
O15123
ncbi mol weight :
56,848 Da
ncbi pathways :
Angiopoietin Receptor Tie2-mediated Signaling Pathway (137917); Cell Surface Interactions At The Vascular Wall Pathway (106062); HIF-1 Signaling Pathway (695200); Hemostasis Pathway (106028); PI3K-Akt Signaling Pathway (692234); PI3K-Akt Signaling Pathway (692979); Rap1 Signaling Pathway (868086); Rap1 Signaling Pathway (878042); Ras Signaling Pathway (868085); Tie2 Signaling Pathway (106063)
ncbi summary :
The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
ANGPT2: Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. Interacts with TEK/TIE2, competing for the same binding site as ANGPT1. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 8p23.1. Cellular Component: extracellular space; cell projection; plasma membrane; extracellular region; nucleus. Molecular Function: protein binding; metal ion binding; receptor tyrosine kinase binding; receptor binding. Biological Process: Tie receptor signaling pathway; organ regeneration; maternal process involved in pregnancy; negative regulation of blood vessel endothelial cell migration; signal transduction; response to organic cyclic substance; germ cell development; negative regulation of positive chemotaxis; negative regulation of angiogenesis; positive regulation of angiogenesis; response to radiation; response to mechanical stimulus; response to hypoxia; response to glucose stimulus; angiogenesis; response to activity; blood coagulation; leukocyte migration
size1 :
24-Strip-Wells
price1 :
190 USD
size2 :
48-Strip-Wells
price2 :
310
size3 :
96-Strip-Wells
price3 :
355
size4 :
5x96-Strip-Wells
price4 :
1435
size5 :
10x96-Strip-Wells
price5 :
2805
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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