catalog number :
MBS2513164
products type :
ELISA Kit
products full name :
Porcine COL7 (Collagen Type VII) ELISA Kit
products short name :
[COL7]
other names :
[collagen alpha-1(VII) chain; Collagen alpha-1(VII) chain; collagen alpha-1(VII) chain; collagen alpha-1(VII) chain; LC collagen; col7a1; long-chain collagen; procollagen, type VII, alpha 1; collagen, type VII, alpha 1; Long-chain collagen; LC collagen]
products gene name :
[COL7]
other gene names :
[Col7a1; Col7a1; AW209154; LC collagen]
uniprot entry name :
CO7A1_MOUSE
specificity :
This kit recognizes natural and some recombinant Porcine COL7. No Significant cross -reactivity or interference between Porcine COL7and analogues was observed.
storage stability :
Store at 4 degree C.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 0.156-10ng/mL. Sensitivity: Min: 0.094ng/mL; Max: 10ng/mL
other info2 :
Intra-assay Precision: Intra - assay Precision (Precision within an assay): 3 samples with low, middle and high level Porcine COL7 were tested 20times on one plate, respectively. Inter-assay Precision: Inter -assay Precision (Precision between assays): 3 samples with low, middle and high level Porcine COL7 were testedon 3 different plates, 20 replicates in each plate.
products description :
Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Porcine COL7 concentrations in serum, plasma and other biological fluids.
ncbi acc num :
NP_031764.2
ncbi gb acc num :
NM_007738.3
ncbi mol weight :
295,232 Da
ncbi pathways :
Anchoring Fibril Formation Pathway (1110306); Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway (1110305); Collagen Biosynthesis And Modifying Enzymes Pathway (1110304); Collagen Formation Pathway (1110303); Extracellular Matrix Organization Pathway (1110302); Protein Digestion And Absorption Pathway (172853); Protein Digestion And Absorption Pathway (171868)
uniprot summary :
COL7A1: the alpha chain of type VII collagen, an extra-cellular basement membrane protein restricted to the zone beneath stratified squamous epithelia. Type VII collagen fibrils are composed of three identical alpha collagen chains. Forms anchoring fibrils, which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen. Dystrophic epidermolysis bullosa can result from defects in this protein or an autoimmune response made to type VII collagen. Homotrimer. Interacts with MIA3, facilitating its loading into transport carriers and subsequent secretion. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Extracellular matrix; Inhibitor; Secreted. Cellular Component: proteinaceous extracellular matrix; extracellular space; collagen; extracellular region; basement membrane. Molecular Function: serine-type endopeptidase inhibitor activity; identical protein binding; protease inhibitor activity. Biological Process: negative regulation of peptidase activity; cell adhesion
size5 :
10x96-Strip-Wells