Human ABCG1 (ATP Binding Cassette Transporter G1) ELISA Kit | MyBioSource MBS2513142 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human ABCG1 (ATP Binding Cassette Transporter G1) ELISA Kit

catalog :

MBS2513142

quantity :

24-Strip-Wells

price :

215 USD

product information

catalog number :

MBS2513142

products type :

ELISA Kit

products full name :

Human ABCG1 (ATP Binding Cassette Transporter G1) ELISA Kit

products short name :

[ABCG1]

other names :

[ATP-binding cassette sub-family G member 1 isoform 7; ATP-binding cassette sub-family G member 1; ATP-binding cassette sub-family G member 1; ABC transporter 8; ATP-binding cassette transporter 8; ATP-binding cassette transporter member 1 of subfamily G; homolog of Drosophila white; white protein homolog (ATP-binding cassette transporter 8); ATP-binding cassette, sub-family G (WHITE), member 1; ATP-binding cassette transporter 8; White protein homolog]

products gene name :

[ABCG1]

other gene names :

[ABCG1; ABCG1; ABC8; WHITE1; ABC8; WHT1]

uniprot entry name :

ABCG1_HUMAN

reactivity :

Human

sequence length :

663

specificity :

This assay has high sensitivity and excellent specificity for detection of Human ABCG1. No significant cross-reactivity or interference between Human ABCG1 and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Human ABCG1 and all the analogues, therefore, cross reaction may still exist.

storage stability :

Store at 4 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 0.156-10ng/mL. Sensitivity: Min: 0.094ng/mL; Max: 10ng/mL

products description :

Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of ABCG1 in human serum, plasma and other biological fluids. Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human ABCG1. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Human ABCG1 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human ABCG1, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Human ABCG1. You can calculate the concentration of Human ABCG1 in the samples by comparing the OD of the samples to the standard curve.

ncbi gi num :

46592978

ncbi acc num :

NP_997512.1

ncbi gb acc num :

NM_207629.1

uniprot acc num :

P45844

ncbi mol weight :

86,628 Da

ncbi pathways :

ABC Transporters Pathway (83035); ABC Transporters Pathway (436); ABC-family Proteins Mediated Transport Pathway (106573); ABCA Transporters In Lipid Homeostasis Pathway (477112); HDL-mediated Lipid Transport Pathway (106158); Lipid Digestion, Mobilization, And Transport Pathway (106111); Lipoprotein Metabolism Pathway (106156); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Nuclear Receptors In Lipid Metabolism And Toxicity Pathway (198887)

ncbi summary :

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified. [provided by RefSeq, Jul 2008]

uniprot summary :

ABCG1: Transporter involved in macrophage lipid homeostasis. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages. Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily. 8 isoforms of the human protein are produced by alternative splicing. Protein type: Transporter, ABC family; Membrane protein, integral; Membrane protein, multi-pass; Transporter. Chromosomal Location of Human Ortholog: 21q22.3. Cellular Component: nucleoplasm; Golgi membrane; Golgi apparatus; endoplasmic reticulum membrane; recycling endosome; intracellular membrane-bound organelle; mitochondrion; integral to plasma membrane; plasma membrane; endosome; external side of plasma membrane. Molecular Function: protein dimerization activity; protein binding; protein homodimerization activity; phospholipid transporter activity; protein heterodimerization activity; cholesterol transporter activity; toxin transporter activity; cholesterol binding; sterol-transporting ATPase activity; phospholipid binding; ADP binding; ATP binding. Biological Process: cholesterol metabolic process; detection of hormone stimulus; response to high density lipoprotein stimulus; positive regulation of cholesterol biosynthetic process; lipoprotein metabolic process; intracellular cholesterol transport; cholesterol efflux; response to lipid; response to organic substance; cholesterol homeostasis; amyloid precursor protein catabolic process; reverse cholesterol transport; regulation of transcription, DNA-dependent; phospholipid efflux; transmembrane transport; phospholipid homeostasis

size1 :

24-Strip-Wells

price1 :

215 USD

size2 :

48-Strip-Wells

price2 :

410

size3 :

96-Strip-Wells

price3 :

490

size4 :

5x96-Strip-Wells

price4 :

2040

size5 :

10x96-Strip-Wells

price5 :

3590