Mouse BMP-6 (Bone Morphogenetic Protein 6) ELISA Kit | MyBioSource MBS2513110 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse BMP-6 (Bone Morphogenetic Protein 6) ELISA Kit

catalog :

MBS2513110

quantity :

24-Strip-Wells

price :

190 USD

product information

catalog number :

MBS2513110

products type :

ELISA Kit

products full name :

Mouse BMP-6 (Bone Morphogenetic Protein 6) ELISA Kit

products short name :

[BMP-6]

other names :

[bone morphogenetic protein 6 preproprotein; Bone morphogenetic protein 6; bone morphogenetic protein 6; BMP-6; VG-1-R; VG-1-related protein; VGR-1; Vg1-related sequence; vegetal related growth factor (TGFB-related); vegetal-related (TGFB related) cytokine; bone morphogenetic protein 6; VG-1-related protein; VG-1-R; VGR-1]

products gene name :

[BMP-6]

other gene names :

[BMP6; BMP6; VGR; VGR1; VGR; BMP-6; VG-1-R; VGR-1]

uniprot entry name :

BMP6_HUMAN

reactivity :

Mouse

sequence length :

513

specificity :

This kit recognizes Mouse Bcl-2 in samples. No significant cross-reactivity or interference between Mouse Bcl-2and analogues was observed.

storage stability :

Store at 4 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma And Other Biological Fluids. Assay Type: Quantitative Sandwich. Detection Range: 15.63-1000pg/mL. Sensitivity: 9.38pg/mL.

products description :

Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Mouse Bcl-2 concentrations in serum, plasma and other biological fluids. Principle of the Assay: This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Mouse Bcl-2. Standards or samples are added to the micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Mouse Bcl-2 and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Mouse Bcl-2, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Mouse Bcl-2. You can calculate the concentration of Mouse Bcl-2 in the samples by comparing the OD of the samples to the standard curve.

ncbi gi num :

4502425

ncbi acc num :

NP_001709.1

ncbi gb acc num :

NM_001718.4

uniprot acc num :

P22004

ncbi mol weight :

57,226 Da

ncbi pathways :

BMP Receptor Signaling Pathway (137948); BMP Signaling Pathway (1084755); BMP Signaling Pathway (1108218); Endochondral Ossification Pathway (198812); Hippo Signaling Pathway (749777); Hippo Signaling Pathway (750388); Id Signaling Pathway (198871); Ovarian Steroidogenesis Pathway (790011); Ovarian Steroidogenesis Pathway (795173); TGF-beta Signaling Pathway (83064)

ncbi summary :

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity. [provided by RefSeq, Jul 2008]

uniprot summary :

BMP6: Induces cartilage and bone formation. Belongs to the TGF-beta family. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 6p24-p23. Cellular Component: extracellular space; cytoplasm. Molecular Function: growth factor activity; protein heterodimerization activity; cytokine activity; transforming growth factor beta receptor binding. Biological Process: cellular iron ion homeostasis; response to glucocorticoid stimulus; BMP signaling pathway; regulation of apoptosis; response to magnesium ion; positive regulation of endothelial cell differentiation; positive regulation of aldosterone biosynthetic process; male genitalia development; kidney development; inflammatory response; skeletal development; response to iron ion; endochondral ossification; response to retinoic acid; positive regulation of bone mineralization; osteoblast differentiation; positive regulation of osteoblast differentiation; positive regulation of chondrocyte differentiation; positive regulation of protein secretion; eye development; regulation of MAPKKK cascade; cartilage development; positive regulation of endothelial cell proliferation; immune response; positive regulation of transcription from RNA polymerase II promoter; response to activity; positive regulation of neuron differentiation; positive regulation of epithelial cell proliferation; growth

size1 :

24-Strip-Wells

price1 :

190 USD

size2 :

48-Strip-Wells

price2 :

310

size3 :

96-Strip-Wells

price3 :

355

size4 :

5x96-Strip-Wells

price4 :

1435

size5 :

10x96-Strip-Wells

price5 :

2805