Human L1CAM/CD171 (L1-Cell Adhesion Molecule) ELISA Kit | MyBioSource MBS2512676 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human L1CAM/CD171 (L1-Cell Adhesion Molecule) ELISA Kit

catalog :

MBS2512676

quantity :

24-Strip-Wells

price :

215 USD

product information

catalog number :

MBS2512676

products type :

ELISA Kit

products full name :

Human L1CAM/CD171 (L1-Cell Adhesion Molecule) ELISA Kit

products short name :

[L1CAM/CD171]

other names :

[L1CAM protein, partial; Neural cell adhesion molecule L1; neural cell adhesion molecule L1; antigen identified by monoclonal antibody R1; L1 cell adhesion molecule; CD_antigen: CD171]

products gene name :

[L1CAM/CD171]

other gene names :

[L1CAM; L1CAM; S10; HSAS; MASA; MIC5; SPG1; CAML1; CD171; HSAS1; N-CAML1; NCAM-L1; N-CAM-L1; CAML1; MIC5; N-CAM-L1; NCAM-L1]

uniprot entry name :

L1CAM_HUMAN

reactivity :

Human

sequence length :

449

specificity :

This kit recognizes natural and recombinant Human L1CAM/CD171. No significant cross-reactivity or interference between Human L1CAM/CD171 and analogues was observed.

storage stability :

Store at 4 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 93.75-6000pg/mL. Sensitivity: Min: 56.25pg/mL; Max: 6000pg/mL

products description :

Intended Uses This ELISA kit applies to the in vitro quantitative determination of Human L1CAM/CD171 concentrations in serum, plasma and other biological fluids. Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to L1CAM/CD171. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for L1CAM/CD171 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain L1CAM/CD171, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of L1CAM/CD171. You can calculate the concentration of L1CAM/CD171 in the samples by comparing the OD of the samples to the standard curve.

ncbi gi num :

19388023

ncbi acc num :

AAH25843.1

uniprot acc num :

P32004

ncbi mol weight :

138,908 Da

ncbi pathways :

Axon Guidance Pathway (83065); Axon Guidance Pathway (476); Axon Guidance Pathway (105688); Basigin Interactions Pathway (106065); Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Cell Surface Interactions At The Vascular Wall Pathway (106062); Developmental Biology Pathway (477129); Hemostasis Pathway (106028); Interaction Between L1 And Ankyrins Pathway (161005)

ncbi summary :

The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons. [provided by RefSeq, May 2013]

uniprot summary :

NCAM-L1: cell adhesion molecule with an important role in the development of the nervous system. Involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Binds to axonin on neurons. Two splice-variant isoforms have been described. Protein type: Membrane protein, integral; Cell adhesion. Chromosomal Location of Human Ortholog: Xq28. Cellular Component: presynaptic membrane; cell surface; focal adhesion; plasma membrane; integral to membrane; terminal button; external side of plasma membrane. Molecular Function: integrin binding; identical protein binding; protein self-association; sialic acid binding. Biological Process: nervous system development; axon guidance; positive regulation of calcium-mediated signaling; chemotaxis; heterophilic cell adhesion; leukocyte adhesion; cell surface receptor linked signal transduction; cell-cell adhesion mediated by integrin; homotypic cell-cell adhesion; positive regulation of cell-cell adhesion; blood coagulation; homophilic cell adhesion; cell adhesion; leukocyte migration. Disease: Hydrocephalus Due To Congenital Stenosis Of Aqueduct Of Sylvius; Corpus Callosum, Partial Agenesis Of, X-linked; Masa Syndrome

size1 :

24-Strip-Wells

price1 :

215 USD

size2 :

48-Strip-Wells

price2 :

410

size3 :

96-Strip-Wells

price3 :

490

size4 :

5x96-Strip-Wells

price4 :

2040

size5 :

10x96-Strip-Wells

price5 :

3590