Rabbit NOS3/eNOS (Nitric Oxide Synthase 3, Endothelial) ELISA Kit | MyBioSource MBS2512482 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Rabbit NOS3/eNOS (Nitric Oxide Synthase 3, Endothelial) ELISA Kit

catalog :

MBS2512482

quantity :

24-Strip-Wells

price :

210 USD

product information

catalog number :

MBS2512482

products type :

ELISA Kit

products full name :

Rabbit NOS3/eNOS (Nitric Oxide Synthase 3, Endothelial) ELISA Kit

products short name :

[NOS3/eNOS]

other names :

[nitric oxide synthase, endothelial isoform 1; Nitric oxide synthase, endothelial; nitric oxide synthase, endothelial; EC-NOS; NOS type III; NOSIII; cNOS; constitutive NOS; endothelial NOS; nitric oxide synthase 3 transcript variant eNOS-delta20; nitric oxide synthase 3 transcript variant eNOS-delta20-21; nitric oxide synthase 3 transcript variant eNOS-delta21; nitric oxide synthase 3 (endothelial cell); Constitutive NOS; cNOS; EC-NOS; Endothelial NOS; eNOS; NOS type III; NOSIII]

products gene name :

[NOS3/eNOS]

other gene names :

[NOS3; NOS3; eNOS; ECNOS; cNOS; eNOS; NOSIII]

uniprot entry name :

NOS3_HUMAN

reactivity :

Rabbit

sequence length :

1203

specificity :

This kit recognizes natural and recombinantRabbitNOS3/eNOS. No significant cross-reactivity or interference between RabbitNOS3/eNOS and analogues was observed.

storage stability :

Store at 4 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 15.625-1000pg/mL. Sensitivity: Min: 9.375pg/mL; Max: 1000pg/mL

other info2 :

Intra-assay Precision: Intra -assay Precision (Precision within an assay): 3 samples with low, middle and high level Human UCHL1 were tested 20times on one plate, respectively. Inter-assay Precision: Inter -assay Precision (Precision between assays): 3 samples with low, middle and high level Human UCHL1 were testedon 3 different plates, 20 replicates in each plate.

products description :

Intended Uses: This ELISA kit applies to the invitro quantitative determination of RabbitNOS3/eNOSconcentrations in serum, plasma and other biological fluids.

ncbi gi num :

40254422

ncbi acc num :

NP_000594.2

ncbi gb acc num :

NM_000603.4

uniprot acc num :

P29474

ncbi mol weight :

67,876 Da

ncbi pathways :

ACE Inhibitor Pathway (198763); AGE/RAGE Pathway (698754); Angiogenesis Pathway (198772); Angiopoietin Receptor Tie2-mediated Signaling Pathway (137917); Arginine And Proline Metabolism Pathway (82957); Arginine And Proline Metabolism Pathway (323); Calcium Signaling Pathway (83050); Calcium Signaling Pathway (459); Corticotropin-releasing Hormone Pathway (920957); Disease Pathway (530764)

ncbi summary :

Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

uniprot summary :

eNOS: endothelial constitutive nitric oxide synthase. Synthesizes nitric oxide (NO) from arginine and oxygen, which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. Induced in humans by caloric restriction. Stimulated by calcium/calmodulin. Inhibited by NOSIP and NOSTRIN. Protein type: EC 1.14.13.39; Amino Acid Metabolism - arginine and proline; Oxidoreductase. Chromosomal Location of Human Ortholog: 7q36. Cellular Component: Golgi membrane; cytoskeleton; cytoplasm; plasma membrane; caveola; nucleus; cytosol. Molecular Function: actin monomer binding; calmodulin binding; protein binding; FAD binding; NADPH-hemoprotein reductase activity; FMN binding; nitric-oxide synthase activity; iron ion binding; heme binding; NADP binding; cadmium ion binding. Biological Process: regulation of systemic arterial blood pressure by endothelin; negative regulation of potassium ion transport; negative regulation of muscle hyperplasia; positive regulation of vasodilation; nitric oxide metabolic process; negative regulation of cell proliferation; negative regulation of hydrolase activity; regulation of the force of heart contraction by chemical signal; regulation of blood pressure; lipopolysaccharide-mediated signaling pathway; negative regulation of blood pressure; angiogenesis; nitric oxide biosynthetic process; regulation of blood vessel size; interaction with host; mitochondrion organization and biogenesis; negative regulation of calcium ion transport; in utero embryonic development; positive regulation of guanylate cyclase activity; regulation of sodium ion transport; ovulation from ovarian follicle; positive regulation of angiogenesis; response to heat; endothelial cell migration; arginine catabolic process; blood vessel remodeling; regulation of nitric-oxide synthase activity; vascular endothelial growth factor receptor signaling pathway; blood coagulation; nitric oxide mediated signal transduction; smooth muscle hyperplasia; lung development. Disease: Preeclampsia/eclampsia 1; Alzheimer Disease; Hypertension, Essential; Stroke, Ischemic

size1 :

24-Strip-Wells

price1 :

210 USD

size2 :

48-Strip-Wells

price2 :

400

size3 :

96-Strip-Wells

price3 :

475

size4 :

5x96-Strip-Wells

price4 :

1975

size5 :

10x96-Strip-Wells

price5 :

3480