Human CETP (Cholesteryl Ester Transfer Protein) ELISA Kit | MyBioSource MBS2511733 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human CETP (Cholesteryl Ester Transfer Protein) ELISA Kit

catalog :

MBS2511733

quantity :

24-Strip-Wells

price :

215 USD

product information

catalog number :

MBS2511733

products type :

ELISA Kit

products full name :

Human CETP (Cholesteryl Ester Transfer Protein) ELISA Kit

products short name :

[CETP]

other names :

[cholesteryl ester transfer protein isoform 2; Cholesteryl ester transfer protein; cholesteryl ester transfer protein; BPI fold containing family F; lipid transfer protein I; cholesteryl ester transfer protein, plasma; Lipid transfer protein I]

products gene name :

[CETP]

other gene names :

[CETP; CETP; BPIFF; HDLCQ10]

uniprot entry name :

CETP_HUMAN

reactivity :

Human

sequence length :

433

specificity :

This kit recognizes natural and recombinant Human CETP. No significant cross-reactivity or interference between Human CETP and analogues was observed.

storage stability :

Store at 4 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 0.313-20ng/mL. Sensitivity: Min: 0.188ng/mL; Max: 20ng/mL

other info2 :

Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Human CETP concentrations in serum, plasma and other biological fluids.

products description :

Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to CETP. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for CETP and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain CETP, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of CETP. You can calculate the concentration of CETP in the samples by comparing the OD of the samples to the standard curve.

ncbi gi num :

554506550

ncbi acc num :

NP_001273014.1

ncbi gb acc num :

NM_001286085.1

uniprot acc num :

P11597

ncbi mol weight :

47,787 Da

ncbi pathways :

HDL-mediated Lipid Transport Pathway (106158); LDL-mediated Lipid Transport Pathway (106159); Lipid Digestion, Mobilization, And Transport Pathway (106111); Lipoprotein Metabolism Pathway (106156); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Orphan Transporters Pathway (1127546); Statin Pathway (198852); Statin Pathway (198363); Transmembrane Transport Of Small Molecules Pathway (106572)

ncbi summary :

The protein encoded by this gene is found in plasma, where it is involved in the transfer of cholesteryl ester from high density lipoprotein (HDL) to other lipoproteins. Defects in this gene are a cause of hyperalphalipoproteinemia 1 (HALP1). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]

uniprot summary :

CETP: Involved in the transfer of insoluble cholesteryl esters in the reverse transport of cholesterol. Defects in CETP are the cause of hyperalphalipoproteinemia type 1 (HALP1). Affected individuals show high levels of alpha-lipoprotein (high density lipoprotein/HDL). Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Lipid-binding; Secreted, signal peptide; Vesicle. Chromosomal Location of Human Ortholog: 16q21. Cellular Component: extracellular space; extracellular region; vesicle. Molecular Function: lipid transporter activity; phospholipid transporter activity; cholesterol transporter activity; cholesterol binding; phosphatidylcholine binding; lipid binding; triglyceride binding. Biological Process: receptor-mediated endocytosis; cholesterol metabolic process; cholesterol transport; lipid homeostasis; lipoprotein metabolic process; lipid transport; phosphatidylcholine metabolic process; cholesterol homeostasis; reverse cholesterol transport; triacylglycerol metabolic process; phospholipid transport; triacylglycerol transport; transmembrane transport; phospholipid homeostasis. Disease: Hyperalphalipoproteinemia 1

size1 :

24-Strip-Wells

price1 :

215 USD

size2 :

48-Strip-Wells

price2 :

410

size3 :

96-Strip-Wells

price3 :

490

size4 :

5x96-Strip-Wells

price4 :

2040

size5 :

10x96-Strip-Wells

price5 :

3590