Mucin 1 (MUC1) | MyBioSource MBS251127 product information

product summary

request information :

company name :

MyBioSource

product type :

protein

product name :

Mucin 1 (MUC1)

catalog :

MBS251127

quantity :

0.01 mg

price :

295 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS251127

products type :

Recombinant Protein

products full name :

Mucin 1 (MUC1)

products short name :

Mucin 1 (MUC1)

other names :

Mucin-1; Mucin-1; mucin-1; episialin; DF3 antigen; H23 antigen; cancer antigen 15-3; krebs von den Lungen-6; mucin 1, transmembrane; carcinoma-associated mucin; polymorphic epithelial mucin; peanut-reactive urinary mucin; tumor associated epithelial mucin; breast carcinoma-associated antigen DF3; tumor-associated epithelial membrane antigen; Medullary cystic kidney disease, autosomal dominant; mucin 1, cell surface associated; Breast carcinoma-associated antigen DF3; Cancer antigen 15-3; CA 15-3; Carcinoma-associated mucin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary mucin; PUM; Polymorphic epithelial mucin; PEM; Tumor-associated epithelial membrane antigen; EMA; Tumor-associated mucin; CD_antigen: CD227Cleaved into the following 2 chains:Mucin-1 subunit alpha; MUC1-NT; MUC1-alpha; Mucin-1 subunit beta; MUC1-betaAlternative name(s):MUC1-CT

products gene name :

MUC1

other gene names :

MUC1; MUC1; EMA; MCD; PEM; PUM; KL-6; MAM6; MCKD; PEMT; CD227; H23AG; MCKD1; MUC-1; ADMCKD; ADMCKD1; CA 15-3; MUC-1/X; MUC1/ZD; MUC-1/SEC; PUM; MUC-1; CA 15-3; KL-6; PUM; PEM; EMA; MUC1-NT; MUC1-alpha; MUC1-beta

uniprot entry name :

MUC1_HUMAN

host :

E Coli

sequence length :

1255

sequence :

MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD GSTSGSGHHH HHHSAGLVPR GSTAIGMKET AAAKFERQHM DSPDLGTGGG SGIEGRGSMG YRGS-YSW MFLMAFALGW RSYRQSSANL LCFAPDLIIN EQRMTLPCMY DQCKHMLYVS SELHRLQVSY EEYLCMKTLL LLSSVPKDGL KSQELFDEIR MTYIKELGKA IVKREGNSSQ NWQRFYQLTK LLDSMHEVVE NLLNYCFQTF LDKTMSIEFP EMLAE

purity :

>95% (SDS-PAGE)

form :

Slippiied as lyophilized form in 20mM Tris, 500mM NaCI, pH8.0, containing lmM EDTA, 1mM Dn, 0.01% sarcosyl, 5% trehalose and preservative.

storage stability :

Store at 2-8Degree C for one month; for long term storage, store at -20 Degree C or -80 Degree C.

tested application :

SD-PAGE; WB; ELISA; IP.

other info1 :

Tag Information: two N-terminal Tags, His-tag and GST-tag. Accession #: P15941. Residues: Serl098~Leu1255. Organism: Homo sapiens (Human). Endotoxin Level: Reconstitute in ddH 2 O

other info2 :

Actual Molecular Mass: 25kDa as determined by SDS-PAGE reducing conditions. Note: Actual band size may differ from predicted due to:. - splice variants: Alternative splicing may create different sized proteins from the same gene. -Relative charge: The composition of amino acids may affect the charge of the protein. - Post-translational modification: Phosphorylation, glycosylation, methylation, etc. -Post-translational cleavage: Many proteins are synthesized as pro-proteins, and then cleaved to give the active form. -Polymerization of the target protein: Dimerization, multimerization, etc.

ncbi gi num :

296439295

ncbi acc num :

P15941.3

ncbi mol weight :

43.3kDa

ncbi pathways :

IL-7 Signaling Pathway 198857!!Metabolism Of Proteins Pathway 106230!!O-linked Glycosylation Pathway 980459!!O-linked Glycosylation Of Mucins Pathway 530747!!Post-translational Protein Modification Pathway 161012!!Termination Of O-glycan Biosynthesis Pathway 530748

ncbi summary :

This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011]

size :

0.01 mg

price :

295 USD

more info or order :

MyBioSource product webpage