Human GPER1 (G Protein Coupled Estrogen Receptor 1) ELISA Kit | MyBioSource MBS2511109 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human GPER1 (G Protein Coupled Estrogen Receptor 1) ELISA Kit

catalog :

MBS2511109

quantity :

24-Strip-Wells

price :

215 USD

product information

catalog number :

MBS2511109

products type :

ELISA Kit

products full name :

Human GPER1 (G Protein Coupled Estrogen Receptor 1) ELISA Kit

products short name :

[GPER1]

other names :

[G-protein coupled estrogen receptor 1; G-protein coupled estrogen receptor 1; G-protein coupled estrogen receptor 1; G protein-coupled receptor 30; IL8-related receptor DRY12; chemoattractant receptor-like 2; chemokine receptor-like 2; constitutively expressed peptide-like receptor; flow-induced endothelial G-protein coupled receptor 1; heptahelix receptor; leucine rich protein in GPR30 3'UTR; lymphocyte-derived G-protein coupled receptor; membrane estrogen receptor; G protein-coupled estrogen receptor 1; Chemoattractant receptor-like 2; Flow-induced endothelial G-protein coupled receptor 1; FEG-1; G protein-coupled estrogen receptor 1; G-protein coupled receptor 30; GPCR-Br; IL8-related receptor DRY12; Lymphocyte-derived G-protein coupled receptor; LYGPR; Membrane estrogen receptor; mER]

products gene name :

[GPER1]

other gene names :

[GPER1; GPER1; mER; CEPR; GPER; DRY12; FEG-1; GPR30; LERGU; LyGPR; CMKRL2; LERGU2; GPCR-Br; CEPR; CMKRL2; DRY12; GPER; GPR30; FEG-1; LYGPR; mER]

uniprot entry name :

GPER1_HUMAN

reactivity :

Human

sequence length :

375

specificity :

This kit recognizes Human GM1-Ab in samples. No Significant cross-reactivity or interference between Human GM1-Ab and analogues was observed.

storage stability :

Store at 4 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma And Other Biological Fluids. Assay Type: Quantitative Sandwich. Detection Range: 1.56-100 mIU/mL. Sensitivity: 0.94 mIU/mL

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): 3 samples with low, mid range and high level Human GM1-Ab were tested 20 times on one plate, respectively. Inter-assay Precision: Inter-assay Precision (Precision between assays): 3 samples with low, mid range and high level Human GM1-Ab were tested on 3 different plates, 20 replicates in each plate.

products description :

Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Human GM1-Ab concentrations in serum, plasma and other biological fluids. Principle of the Assay: This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antigen specific to Human GM1-Ab. Standards or samples are added to the micro ELISA plate wells and combined with the specific antigen. Then a biotinylated detection antigen specific for Human GM1-Ab and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human GM1-Ab, biotinylated detection antigen and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Human GM1-Ab. You can calculate the concentration of Human GM1-Ab in the samples by comparing the OD of the samples to the standard curve.

ncbi gi num :

148228791

ncbi acc num :

NP_001091671.1

ncbi gb acc num :

NM_001098201.1

uniprot acc num :

Q99527

ncbi mol weight :

42,248 Da

ncbi pathways :

Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway (1127664); Disease Pathway (530764); Estrogen Signaling Pathway (799177); Estrogen Signaling Pathway (198863); Estrogen Signaling Pathway (799197); G Alpha (i) Signalling Events Pathway (119550); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); GPCRs, Class A Rhodopsin-like Pathway (198886)

ncbi summary :

This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized. [provided by RefSeq, Jul 2008]

uniprot summary :

GPER1: Receptor for estrogen. Belongs to the G-protein coupled receptor 1 family. Protein type: Membrane protein, multi-pass; Membrane protein, integral; Motility/polarity/chemotaxis; GPCR, family 1; Receptor, GPCR. Chromosomal Location of Human Ortholog: 7p22.3. Cellular Component: Golgi apparatus; endoplasmic reticulum membrane; cytoplasmic vesicle membrane; endoplasmic reticulum; integral to plasma membrane; early endosome; postsynaptic density; dendrite; nuclear envelope; trans-Golgi network; Golgi membrane; presynaptic membrane; recycling endosome; perinuclear region of cytoplasm; axon; mitochondrial membrane; cytoplasm; keratin filament; plasma membrane; presynaptic active zone; dendritic shaft; nerve terminal; intracellular; cell junction; nucleus. Molecular Function: G-protein coupled receptor activity; protein binding; estrogen receptor activity; mineralocorticoid receptor activity; chromatin binding; steroid binding. Biological Process: positive regulation of apoptosis; generation of action potential; nuclear fragmentation during apoptosis; positive regulation of caspase activity; positive regulation of vasodilation; negative regulation of DNA metabolic process; positive regulation of neurotransmitter secretion; negative regulation of leukocyte activation; negative regulation of cell proliferation; elevation of cytosolic calcium ion concentration; positive regulation of MAPKKK cascade; positive regulation of epidermal growth factor receptor signaling pathway; positive regulation of cAMP biosynthetic process; positive regulation of cell proliferation; inflammatory response; steroid hormone receptor signaling pathway; positive regulation of neurogenesis; cytosolic calcium ion homeostasis; negative regulation of lipid biosynthetic process; positive regulation of insulin secretion; positive regulation of inositol trisphosphate biosynthetic process; apoptotic chromosome condensation; negative regulation of fat cell differentiation; cell cycle; positive regulation of phosphoinositide 3-kinase cascade; G-protein coupled receptor protein signaling pathway; mineralocorticoid receptor signaling pathway; negative regulation of inflammatory response; positive regulation of G-protein coupled receptor protein signaling pathway; innate immune response; steroid hormone mediated signaling; positive regulation of transcription from RNA polymerase II promoter; positive regulation of release of sequestered calcium ion into cytosol; positive regulation of protein amino acid phosphorylation; positive regulation of cell migration

size1 :

24-Strip-Wells

price1 :

215 USD

size2 :

48-Strip-Wells

price2 :

410

size3 :

96-Strip-Wells

price3 :

490

size4 :

5x96-Strip-Wells

price4 :

2040

size5 :

10x96-Strip-Wells

price5 :

3590