Mouse PVRL2 (Poliovirus Receptor Related Protein 2) ELISA Kit | MyBioSource MBS2510611 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse PVRL2 (Poliovirus Receptor Related Protein 2) ELISA Kit

catalog :

MBS2510611

quantity :

48-Strip-Wells

price :

410 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS2510611

products type :

ELISA Kit

products full name :

Mouse PVRL2 (Poliovirus Receptor Related Protein 2) ELISA Kit

products short name :

PVRL2

other names :

nectin-2 isoform delta; Nectin-2; nectin-2; herpesvirus entry protein B; poliovirus receptor-like 2; poliovirus receptor-related 2 (herpesvirus entry mediator B); Herpes virus entry mediator B; Herpesvirus entry mediator B; HveB; Poliovirus receptor-related protein 2; CD_antigen: CD112

products gene name :

PVRL2

other gene names :

PVRL2; PVRL2; HVEB; PRR2; CD112; PVRR2; HVEB; PRR2; Herpesvirus entry mediator B; HveB

uniprot entry name :

PVRL2_HUMAN

reactivity :

Mouse

sequence length :

538

specificity :

This kit recognizes natural and recombinant Mouse PVRL2. No significant cross-reactivity or interference between Mouse PVRL2 and analogues was observed.

storage stability :

Store at 4 degree C.

other info1 :

Samples: Serum, plasma and other biological fluids. Assay Type: Sandwich. Detection Range: 78.125-5000pg/mL. Sensitivity: The minimum detectable dose of Mouse PVRL2 is 46.875pg/mL (The sensitivity of this assay, or lowest detectable limit (LDL) was defined as the lowest protein concentration that could be differentiated from zero).

other info2 :

Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Mouse PVRL2 concentrations in serum, plasma and other biological fluids.

products description :

Principle of the assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to PVRL2. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for PVRL2 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain PVRL2, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of PVRL2. You can calculate the concentration of PVRL2 in the samples by comparing the OD of the samples to the standard curve.

ncbi gi num :

112789532

ncbi acc num :

NP_001036189.1

ncbi gb acc num :

NM_001042724.1

uniprot acc num :

Q92692

ncbi mol weight :

51,359 Da

ncbi pathways :

Adaptive Immune System Pathway (366160); Adherens Junction Pathway (83070); Adherens Junction Pathway (481); Adherens Junctions Interactions Pathway (119533); Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Cell Junction Organization Pathway (160966); Cell-Cell Communication Pathway (477132); Cell-cell Junction Organization Pathway (119532); Herpes Simplex Infection Pathway (377873)

ncbi summary :

This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

uniprot summary :

nectin 2: Probable cell adhesion protein. Belongs to the nectin family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Cell adhesion. Chromosomal Location of Human Ortholog: 19q13.2. Cellular Component: focal adhesion; cell surface; integral to membrane; plasma membrane; intercellular junction; zonula adherens. Molecular Function: viral receptor activity; identical protein binding; protein binding; protein homodimerization activity; coreceptor activity; cell adhesion molecule binding. Biological Process: establishment of mitochondrion localization; acrosome formation; intercellular junction assembly and maintenance; regulation of immune response; sperm mitochondrion organization and biogenesis; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; positive regulation of immunoglobulin mediated immune response; spermatid nuclear differentiation; cytoskeleton organization and biogenesis; susceptibility to natural killer cell mediated cytotoxicity; virion attachment, binding of host cell surface coreceptor; signal transduction; positive regulation of natural killer cell mediated cytotoxicity; positive regulation of mast cell activation; viral envelope fusion with host membrane; fertilization; cell part morphogenesis; adhesion to host; homophilic cell adhesion; spermatid development

size1 :

48-Strip-Wells

price1 :

410 USD

size2 :

96-Strip-Wells

price2 :

490

more info or order :

MyBioSource product webpage